Toxic epidermal necrolysis related to Cisplatin and pemetrexed for metastatic non-small cell lung cancer.

Background: Toxic epidermal necrolysis (TEN) is an uncommon but life-threatening adverse drug reaction. Pemetrexed is a multitargeted antifolate. It was first used in combination with cisplatin as a front-line treatment for malignant pleural mesothelioma.