Measurement of plasma protein and whole body protein metabolism using [N]glycine in a young adult man - a pilot study.

A novel simplified method is presented for the estimation of the metabolism of plasma proteins (albumin, fibrinogen, , and -globulin, glycoprotein) with regard to the whole body protein metabolism in a young male volunteer (22 years, 81 kg body mass). This method is based on multiple oral administration of [N]glycine followed by measurement of N in plasma proteins, total free amino acids, urea and excreted urinary N. The fractional synthesis rate of albumin was estimated to 6.

Tracer kinetics and metabolic models in medicine.

In the present paper, a survey of methods applied to the interpretation and evaluation of tracer kinetic data is given. For their mathematical description, both compartmental and non-compartmental models, such as the modified model of Sprinson and Rittenberg, the San Pietro-Rittenberg model, two models of the albumin metabolism and a 10-pool model of the N and protein metabolism were used. By means of single or multiple pulse, infusion and priming techniques, the N and protein metabolism in various metabolic states (e.

Studies of the protein and the energy metabolism in man during a wintering in Antarctica.

During the 29th Soviet Antarctic Expedition in Novolazarevskaya from March 1984 to March 1985, the protein and energy metabolisms were studied in six expeditioners from the German Democratic Republic. The investigations were carried out at the beginning of the expedition (May), during the polar night (July) and during the polar day (December). The effect of a special stress situation (sledge trek in April 1984) was investigated in one subject.