Ocular Surface Homeostasis After Scleral Lens Usage.

Objectives: The aim of this prospective study is to examine the effects of 5 hours of well-fitted, mini-scleral contact lens (mini-SL) wear on the tear film cytokine expression in healthy eyes.

Methods: Twenty-three healthy participants were included in the study. One eye of each participant was selected at random, and a mini-SL measuring 16.

Interleukin-6 in Critical Coronavirus Disease 2019, a Driver of Lung Inflammation of Systemic Origin?

Unlabelled: To examine whether interleukin-6 in critical coronavirus disease 2019 is higher in arterial than in central venous blood, as a sign of predominantly local pulmonal rather than systemic interleukin-6 production.

Design: Prospective cohort pilot study with repeated weekly measurements of interleukin-6 in arterial and central venous blood. Respiratory function, assessed with Pao/Fio ratio, was measured at the time of blood sampling.