Publications by authors named "Hanqiao Zhang"

The diamondback moth (Plutella xylostella L.), a notorious pest infesting cruciferous vegetables worldwide, has developed a high level of resistance to various commonly used chemical pesticides. In this paper, we explore whether dopa decarboxylase (DDC), which is essential for survival and development in insects, could be used as a potential target for the control of P.

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has developed high levels of resistance to many commonly used insecticides. () is essential for insect survival; thus, we evaluated whether could be a potential target for controlling . In this study, was identified; further qPCR analysis showed that increased its expression during larval pupation and was highly expressed in the head and epidermis of prepupa in .

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Article Synopsis
  • This study focused on creating deep-learning radiomics models using optical coherence tomography (OCT) scans to assess thyroid eye disease activity in 33 patients with 66 affected eyes.
  • Patients were classified into active and inactive groups based on their clinical activity scores, and OCT scans were analyzed to extract relevant features using advanced statistical methods.
  • The study found that the support vector machine (SVM) model had better performance for choroid features (AUC of 0.813) compared to retinal features in predicting disease activity, suggesting OCT-based analysis could improve clinical evaluations.
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A major QTL, qLF2.1, for flowering time in tomatoes, was fine mapped to chromosome 2 within a 51.37-kb interval, and the SlJMJ14 gene was verified as the causal gene by knockout.

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We explore when and why large classes of proteins expand into new sequence space. We used an unsupervised machine learning approach to observe the sequence landscape of REC domains of bacterial response regulator proteins. We find that within-gene recombination can switch effector domains and, consequently, change the regulatory context of the duplicated protein.

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Purpose: To describe the prevalence, distribution, and features of anterior and posterior segment abnormalities in the contralateral eye in cases unilateral of anophthalmia and blind microphthalmia.

Methods: The medical records of patients with unilateral congenital anophthalmia and blind microphthalmia referred to Beijing Tongren Hospital between January 2017 and December 2021 were reviewed retrospectively to investigate the prevalence of abnormalities of the fellow eye.

Results: A total of 168 patients were included.

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Bifenazate is a novel acaricide that has been widely used to control spider mites. Interestingly, we found bifenazate had a biological activity against the diamondback moth (), one of the most economically important pests on crucifer crops around the world. However, the molecular mechanisms underlying the response of to bifenazate treatment are not clear.

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Article Synopsis
  • The study aims to create a random forest model for detecting active and quiescent phases in patients with Graves Orbitopathy (GO).
  • It included 243 patients and used various clinical characteristics as predictors, comparing the model's effectiveness against logistic regression and other machine learning methods.
  • The random forest model demonstrated better accuracy and reliability in detecting GO activity, achieving high sensitivity and specificity compared to other models.
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This study aimed to describe the correlation between some clinical features and orbital soft tissue volume in Graves orbitopathy (GO). The authors collected computed tomography scans from 56 untreated GO patients and measured fat volume (FV), intraorbital and extraorbital FV (IFV, EFV), bony cavity volume (BV), and extraocular muscle volume (MV) of the 112 orbits by using Mimics software. The ratio of soft tissue volume and BV were used to eliminate the individual variations.

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Background: Studies on the factors related to lacrimal gland prolapse (LGP) in patients with thyroid-associated ophthalmopathy (TAO) are limited. This study aimed to assess the factors associated with LGP on magnetic resonance imaging (MRI) and its relation to TAO activity .

Methods: Thirty-six patients (72 orbits) with inactive TAO (43 orbits, Clinical Activity Score [CAS] < 3) or active TAO (29 orbits, CAS ≥3) were investigated retrospectively.

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Pesticides have been used extensively in the field of plant protection to maximize crop yields. However, the long-term, unmanaged application of pesticides has posed severe challenges such as pesticide resistance, environmental contamination, risk in human health, soil degradation, and other important global issues. Recently, the combination of nanotechnology with plant protection strategies has offered new perspectives to mitigate these global issues, which has promoted a rapid development of NCs-based pesticides.

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Viruses are ubiquitous microbiome components, shaping ecosystems via strain-specific predation, horizontal gene transfer and redistribution of nutrients through host lysis. Viral impacts are important in groundwater ecosystems, where microbes drive many nutrient fluxes and metabolic processes; however, little is known about the diversity of viruses in these environments. We analyzed four groundwater plasmidomes (the entire plasmid content of an environment) and identified 200 viral sequences, which clustered into 41 genus-level viral clusters (approximately equivalent to viral genera) including 9 known and 32 putative new genera.

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Background: Currently, spectral-domain optical coherence tomography (SD-OCT) appears to be a new type of glaucoma diagnostic tool. Thus, this study aimed to evaluate the effectiveness of glaucoma diagnostic parameters from SD-OCT of patients with different severities of myopia.

Methods: This was a cross-sectional study.

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During the synthesis of abiraterone acetate bulk drug in some laboratory batches, two unreported impurities were detected by high-performance liquid chromatography analysis at levels ranging from 0.05 to 0.10% according to the United States Pharmacopeia method.

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An on-chip microwave interferometer suitable for high-sensitivity nanoscale magnetic material characterization is proposed. The device cancels the background parasitic common mode noise automatically. The magnetization dynamics of a 240 nm wide, 5 μm long, and 70 nm thick single permalloy nanowire is investigated.

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We propose and demonstrate a simple, ultra sensitive radio frequency (RF) sensor to detect a single yeast cell and distinguish its viability in a microfluidic channel. On-chip interference is used to cancel background probing signals to improve sensor sensitivity. Individual viable and nonviable yeast cells (approximately 5.

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