Publications by authors named "Hanqiang Jin"
Human cadaveric tissues are essential for biomechanical research, however, omitting statements regarding the ethical implications remains very common in many recent articles of biomechanics. We systematically searched PubMed for research articles published from 2017 to 2022 to identify all relevant studies (n=1850). Information on the characteristics of the cadaveric specimens and the acquisition of ethical approval was collected.
View Article and Find Full Text PDFObjective: Obesity is a risk factor for knee osteoarthritis (KOA) development and progression. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are indicated for type 2 diabetes mellitus (T2DM) and obesity. However, whether KOA patients can benefit from GLP-1RA therapies has not been sufficiently investigated, especially in the long term.
View Article and Find Full Text PDFGlycosylation is an important modification of membrane proteins that results in functional changes in many cellular activities, from cell-cell recognition to regulatory signaling. Fucosyltransferase 8 (FUT8) is the sole enzyme responsible for core fucosylation, and aberrant fucosylation by dysregulated expression of fucosyltransferases is responsible for the growth of various types of carcinomas. However, the function of FUT8 in the progress of osteosarcoma (OS) has not been reported.
View Article and Find Full Text PDFArticle Synopsis
- Scientists are studying a type of bone tumor called giant cell tumor of bone (GCTB) that often comes back after treatment. They want to find out what features show how likely it is for the tumor to return after surgery.
- They looked at CT scans of 124 patients who had this tumor near their knee and checked things like the tumor size and how close it was to important parts of the bone.
- They found that certain details from the scans can help doctors predict if the tumor will come back after treatment, which is important for making better decisions about patient care.
•Preoperative CT images of GCTBs have value in prognostic prediction.•Certain features of GCTBs on CT images are related to local recurrence.•Our models' predictions for GCTB patients accepting extensive curettage are good.
View Article and Find Full Text PDFAims: Methicillin-resistant (MRSA) can cause wound infections via a 'Trojan Horse' mechanism, in which neutrophils engulf intestinal MRSA and travel to the wound, releasing MRSA after apoptosis. The possible role of intestinal MRSA in prosthetic joint infection (PJI) is unknown.
Methods: Rats underwent intestinal colonization with green fluorescent protein (GFP)-tagged MRSA by gavage and an intra-articular wire was then surgically implanted.
Background: Previous studies have demonstrated that age, smoking, Tamai's level of amputation, causes of injury and ischemia time were associated with the success rate of digit replantation. The primary objective of this study is to investigate whether mental status including anxiety and depression is associated with the rate of digit replant failure.
Methods: This study included 134 digits from 102 patients who received digital replantation after complete amputation from 1 September 2013 to 1 September 2015.