Publications by authors named "Hannes Max Schwelm"
Drug use is prevalent in prisons with drugs associated with depressant effects found to be more prevalent than stimulants. Synthetic cathinones (SCats; often sold as "bath salts", "ecstasy", "molly", and "monkey dust") are the second largest category of new psychoactive substances (NPS) currently monitored by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) and are commonly used as substitutes for regulated stimulants, such as amphetamine, cocaine, and MDMA. N,N-dimethylpentylone (also known as dimethylpentylone, dipentylone, and bk-DMBDP) was detected for the first time in the Scottish prisons in seven powder samples seized between January and July 2023.
View Article and Find Full Text PDF1-(2,3-Dihydro-1H-inden-5-yl)-2-(piperidin-1-yl)pentan-1-one (3,4-Pr-PipVP), a novel synthetic cathinone (SCat), was first identified in 2022 in Germany. The product was marketed as 1-(bicyclo[4.2.
View Article and Find Full Text PDFArticle Synopsis
- Due to new legal restrictions on fentanyl analogs, acylpiperazine opioids like AP-238 have emerged in the illegal drug market, leading to increased acute intoxications reported by the European Early Warning System.
- A study was conducted to identify metabolites of AP-238 using pooled human liver microsomes and samples from post-mortem examinations, which revealed a total of 32 metabolites formed during metabolism.
- The findings show that the main metabolites are produced through hydroxylation and other reactions, indicating their potential as biomarkers for documenting AP-238 consumption, particularly beneficial for abstinence monitoring.