Publications by authors named "Hanneke Hagenaars"
Article Synopsis
- In the Netherlands, organ donation after euthanasia (DCD-V) has increased since 2012, but the outcomes of kidney transplants from DCD-V donors haven't been fully explored.
- A study aimed to compare the outcomes of DCD-V kidney transplants with those from DCD-III and brain-dead (DBD) donors, analyzing data from 2012 to 2023.
- Results showed that DCD-V kidney transplants had a significantly lower incidence of delayed graft function compared to DCD-III, suggesting DCD-V may be a viable option to expand the kidney donor pool.
Background: In The Netherlands, 60% of deceased-donor kidney offers are after donation after circulatory death. Cold and warm ischemia times are known risk factors for delayed graft function (DGF) and inferior allograft survival. Extraction time is a relatively new ischemia time.
View Article and Find Full Text PDFT-cell immunity in the liver is tightly regulated to prevent chronic liver inflammation in response to antigens and toxins derived from food and intestinal bacterial flora. Since the main sites of T cell activation in response to foreign components entering solid tissues are the draining lymph nodes (LN), we aimed to study whether Antigen-Presenting Cell (APC) subsets in human liver lymph-draining LN show features that may contribute to the immunologically tolerant liver environment. Healthy liver LN, iliac LN, spleen and liver perfusates were obtained from multi-organ donors, while diseased liver LN were collected from explanted patient livers.
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