Publications by authors named "Hanne Slott Jensen"
Multifactorial intervention to prevent cardiovascular disease in patients with early rheumatoid arthritis: protocol for a multicentre randomised controlled trial.
BMJ Open
April 2016
Introduction: Cardiovascular morbidity is a major burden in patients with rheumatoid arthritis (RA). In this study, we compare the effect of a targeted, intensified, multifactorial intervention with that of conventional treatment of modifiable risk factors for cardiovascular disease (CVD) in patients with early RA fulfilling the 2010 American College of Rheumatology European League Against Rheumatism (ACR/EULAR) criteria.
Methods And Analysis: The study is a prospective, randomised, open label trial with blinded end point assessment and balanced randomisation (1:1) conducted in 10 outpatient clinics in Denmark.
Validity and Agreement between the 28-Joint Disease Activity Score Based on C-Reactive Protein and Erythrocyte Sedimentation Rate in Patients with Rheumatoid Arthritis.
Arthritis
January 2015
Objective. To validate the agreement between the 28-joint disease activity score based on erythrocyte sedimentation rate (DAS28-ESR) and the 28-joint disease activity score based on C-reactive protein (DAS28-CRP) in a group of Danish patients with rheumatoid arthritis (RA). Methods.
View Article and Find Full Text PDFAnti-nuclear antibodies (ANA) have traditionally been evaluated using indirect fluorescence assays (IFA) with HEp-2 cells. Quantitative immunoassays (EIA) have replaced the use of HEp-2 cells in some laboratories. Here, we evaluated ANA in 400 consecutive and unselected routinely referred patients using IFA and automated EIA techniques.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to evaluate disease progression and the effectiveness of various assessment methods in patients with polymyalgia rheumatica (PMR) over a 26-week period.
- Eighty-five patients starting treatment with prednisone were monitored for pain, inflammation, and quality of life through clinical exams, laboratory tests, and ultrasound evaluations.
- Results indicated that most patients improved significantly with corticosteroid treatment, and certain ultrasound findings could help predict this response; thus, incorporating specific patient-reported outcomes and inflammatory markers is recommended for better assessment in clinical settings.
2012 Provisional classification criteria for polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative.
Arthritis Rheum
April 2012
Article Synopsis
- - The study aimed to create classification criteria for polymyalgia rheumatica (PMR) that could help differentiate it from similar conditions, using a sample of 125 PMR patients and 169 non-PMR subjects over six months.
- - A scoring system was developed based on specific symptoms, such as morning stiffness and hip pain, with a score of 4 or higher indicating a strong likelihood of PMR, while incorporating ultrasound increased accuracy further.
- - The provisional criteria suggest that patients over 50 with certain symptoms and no alternative diagnosis can be classified as having PMR, but these criteria are intended for classification, not for diagnosis.
Article Synopsis
- - The study aimed to create new classification criteria for polymyalgia rheumatica (PMR) through a cohort of 125 patients with PMR and 169 individuals with similar conditions for comparison.
- - A scoring system was developed based on symptoms like morning stiffness, hip pain, and absence of certain antibodies, achieving a score ≥4 with 68% sensitivity and 78% specificity for identifying PMR.
- - The criteria suggest that patients over 50 with specific symptoms, including bilateral shoulder pain and elevated inflammatory markers, might be classified as having PMR, but these criteria are not intended for making a diagnosis.
We describe a patient with ochronotic spondyloarthropathy who presented with severe spinal stiffness, advanced degenerative changes in the spine with ossifications of the intervertebral discs and subchondral sclerosis of the sacroiliac joints. The diagnosis of ochronosis was verified by detection of homogentisic acid in the urine. Ochronosis is rare, but should be kept in mind as a differential diagnosis to other spondyloarthropathies including AS.
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