Publications by authors named "Hanne M Weidemann"
Article Synopsis
- The lactate receptor HCAR1 is overexpressed in pancreatic ductal adenocarcinoma (PDAC) and is involved in lactate transport between cancer cells.
- Researchers investigated whether miR-431-5p could regulate HCAR1, discovering that miR-431-5p lowers HCAR1 levels by directly binding to its 3' UTR.
- Overexpression of miR-431-5p inhibited cell growth and induced apoptosis in BxPC-3 cells, highlighting its potential role as a tumor suppressor in PDAC.
