Access to Enantiopure Spiropyridines Enabled by Enantio-Relay Double [2 + 2 + 2] Cycloaddition and Kinetic Resolution [2 + 2 + 2] Cycloaddition of Alkynes and Nitriles.

The synthesis of enantiopure and structurally unique spiro-type molecules is of utmost significance in catalysis, synthetic chemistry, and related fields. We present here a general solution, a nickel-catalyzed [2 + 2 + 2] cycloaddition, for accessing enantioenriched spiropyridines from readily available nitriles and alkynes in a single synthetic step, including (1) enantio-relay double [2 + 2 + 2] cycloaddition of malononitriles with alkynes and (2) kinetic resolution [2 + 2 + 2] cycloaddition of racemic pyridine-containing nitriles with alkynes. Both strategies feature a broad substrate scope and exclusive regioselectivities, and are scalable to multigram.

Benefits of Gardenia jasminoides Ellis's floral volatile components on human emotions and moods.

With the advancement of society, there has been an increasing focus on the health status of college students, with plants playing a significant role in the campus environment. Investigating the impact of the aromatic scent of plants on the physical and mental well-being of college students is essential. This study centered on the common indoor potted flower Gardenia jasminoides Ellis to delve into its aroma and the influence of its volatiles on the physical, mental, and emotional recovery of college students.

Re-sintering induced ionic conductivity recovery for air-exposed LiPSCl argyrodite sulfide electrolyte.

One of the most common problems with sulfide solid-state electrolytes is weak water stability. We report a re-sintering method to recover the ionic conductivity of argyrodite LiPSCl solid-state electrolyte, which has been exposed to moisture for 10 h, from 1.06 to 6.

Organic photoredox catalyzed C(sp)-H functionalization of saturated aza-heterocycles a cross-dehydrogenative coupling reaction.

Herein we present a novel protocol to access α-functionalized saturated aza-heterocycles, and a variety of nucleophilic groups, such as indole, naphthol, phenol, pyrrole, furyl, nitromethyl, and cyano, could be easily installed into saturated aza-heterocycles. Furthermore, a range of biologically valuable 3,3'-diindolylmethane derivatives could also be readily accessed under mild photocatalytic conditions.

20 mS cm Li-argyrodite solid electrolyte produced facile high-speed-mixing.

A novel efficient method is proposed to synthesize a large amount of LiPSCl precursor in only 5 minutes with a conductivity of 20 mS cm after sintering, which can replace the common ball-milling method. The ASSBs show excellent electrochemical performance with high loading (20 mg cm) and great capacity retention (80% after 200 cycles). This is important for the industrial production of sulfide solid electrolytes for fabricating Ah-level ASSBs.

Organic photoredox catalyzed dealkylation/acylation of tertiary amines to access amides.

A mild metal-free C-N bond activation strategy for the direct conversion of inert tertiary amines with acyl chlorides into tertiary amides organic photoredox catalysis is presented. In this protocol, a novel organic photocatalyst (Cz-NI-Ph) that showed excellent catalytic performance during C-N bond cleavage is developed. Moreover, this reaction features green and mild conditions, broad substrate scope, and readily available raw materials.

Organic photoredox catalytic amino-heteroarylation of unactivated olefins to access distal amino ketones.

Here we describe a metal-free amino-heteroarylation of unactivated olefins organic photoredox catalysis, providing a concise and efficient approach for the rapid synthesis of various δ (β, ε)-amino ketones under mild conditions. This protocol demonstrates that the new photocatalyst Cz-NI developed by our group has an excellent photoredox catalytic performance. Finally, a series of mechanistic experiments and DFT calculations indicate that this transformation undergoes a photoredox catalytic sequential radical addition/functional group migration process.