Publications by authors named "Hannah Slattery"
Pulmonary fibrosis (PF) is the pathologic accumulation of extracellular matrix components in lung tissue that result in scarring following chronic lung injury. PF is typically diagnosed by high resolution computed tomography (HRCT) and/or invasive biopsy. However, HRCT cannot distinguish old injury from active fibrogenesis.
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- Liver biopsy is the standard for diagnosing NASH but is invasive; this study explored non-invasive MRI techniques to assess liver fibrosis and treatment response in a rat model of NASH.*
- Molecular MRI agents like EP-3533 and Gd-Hyd were used along with MR elastography to evaluate their effectiveness in identifying fibrosis stages and treatment responses over different feeding regimens.*
- Results showed EP-3533 had the highest accuracy in distinguishing fibrotic levels, with Gd-Hyd being the most effective in identifying treatment responders, indicating these MRI methods may provide reliable non-invasive alternatives to biopsies.*
Screening and treatment for hepatitis C virus (HCV) infection were not prioritised in psychiatric patients due to adverse neuropsychiatric effects of interferon therapy despite reports of high prevalence. However, with the safe new antiviral drugs, HCV eradication has become a reality in these patients. The aim of this study was to report HCV seroprevalence, risk factors and treatment model in an Australian cohort.
View Article and Find Full Text PDFTwo patients each developed a single, fixed somatic delusion complicating their existing bipolar disorder. Both failed to respond to a range of antidepressant and antipsychotic medications. They each showed a partial response to clozapine and to electroconvulsive therapy, with resolution of mood symptoms and diminution of their ongoing somatic preoccupation.
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