Publications by authors named "Hannah R Mathieson"
Article Synopsis
- This project analyzed if cranial ischaemic complications in giant cell arteritis (GCA) patients were linked to existing cardiovascular (CV) risk factors, CV diseases, or genetic predispositions.
- The study examined data from 1946 GCA patients, finding that 17% had cranial ischaemic issues, with significant factors including age (especially those ≥80) and hypertension, while anticoagulant therapy seemed to reduce risk.
- The research indicated potential genetic factors affecting CV-related traits and suggested that immune and coagulation pathways may play a role in these complications, warranting further investigation before applying findings to clinical settings.
Article Synopsis
- The study explored how some patients with axial spondyloarthritis (axSpA) experience subjective symptom deterioration before their scheduled doses of three different TNF inhibitors (TNFis): etanercept, adalimumab, and infliximab.
- By analyzing MRI scans and clinical assessments, it was found that many patients showed high disease activity and a notable presence of bone marrow edema (MRI-BMO) before their doses.
- The results indicated that shorter periods between doses correlated with fewer new lesions and improved clinical responses, but further research is necessary to understand the implications of these findings.
Diurnal variation of gait in patients with rheumatoid arthritis: The DIVIGN study.
Clin Biomech (Bristol)
August 2014
Background: Circadian variation of joint stiffness (morning stiffness) and its impact on functional ability are widely recognised in rheumatoid arthritis. Subsequent within-day variation of walking ability is important due to the increased availability of instrumented gait analysis. This study aimed to quantify diurnal variation of gait in patients with rheumatoid arthritis, and explore associations with disease characteristics.
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