Cobalt complexes modulate plasmid conjugation in Escherichia coli and Klebsiella pneumoniae.

Antimicrobial resistance genes (ARG), such as extended-spectrum β-lactamase (ESBL) and carbapenemase genes, are commonly carried on plasmids. Plasmids can transmit between bacteria, disseminate globally, and cause clinically important resistance. Therefore, targeting plasmids could reduce ARG prevalence, and restore the efficacy of existing antibiotics.

Autistic traits and mental health in women with the fragile-X premutation: maternal status versus genetic risk.

Background: Research on women with the fragile-X premutation (FX-p) has been underrepresented within the field of behavioural phenotypes.

Aims: To understand whether the FX-p confers risk for autistic traits, depression and anxiety, independent of maternal status.

Method: In study 1, mothers of children with fragile-X syndrome (M-FXp; n = 51, mean age 43 years (s.