Publications by authors named "Hannah Klaus"
Article Synopsis
- Drug-resistant Mycobacterium tuberculosis, especially mutants resistant to isoniazid, creates significant global health challenges due to mutations in the katG gene, affecting a crucial enzyme.
- Researchers employed CRISPRi, transcriptomics, and metabolomics to identify metabolic and transcriptional changes in an isoniazid-resistant katG mutant, revealing new weaknesses in processes like respiration and ribosome biogenesis.
- The study indicates that these identified vulnerabilities could be targeted for therapeutic strategies, offering potential improvements in treatment effectiveness against drug-resistant tuberculosis strains.
This study investigated the potential of utilising the elemental fingerprinting of honey to differentiate New Zealand (NZ) honey from that of international origin. Twenty elements were analysed by ICP-MS in 352 honeys from 34 various countries. Of these, 323 honeys (245 New Zealand honeys, 78 international) and two subsets of data (NZ and European origin, n = 306, and, NZ and Denmark/Germany, n = 280) were visualised using principal component analysis (PCA).
View Article and Find Full Text PDFDetermination of geographical origin of honey is important to consumers to confirm authenticity. This study investigated the elemental fingerprint of 181 honey samples collected from apiary sites in six regions of North Island, New Zealand to determine if differences were observed due to region of collection or land use surrounding the hive (e.g.
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