Dietary pulses as a means to improve the gut microbiome, inflammation, and appetite control in obesity.

A dysbiotic intestinal microbiome has been linked to chronic diseases such as obesity, which may suggest that interventions that target the microbiome may be useful in treating obesity and its complications. Appetite dysregulation and chronic systemic low-grade inflammation, such as that observed in obesity, are possibly linked with the intestinal microbiome and are potential therapeutic targets for the treatment of obesity via the microbiome. Dietary pulses (e.

Biomechanical Comparison of Adjustable-Loop Femoral Cortical Suspension Devices for Soft Tissue ACL Reconstruction.

Background: Several new adjustable-loop devices (ALDs) for anterior cruciate ligament reconstruction (ACLR) have not been tested in vitro.

Purpose: To compare the biomechanical performances of 5 ALDs under a high cyclic load and forces representative of the return-to-play conditions seen in the recovering athlete.

Study Design: Controlled laboratory study.

The importance of neurology and genetic testing in the patient with non-cleft velopharyngeal dysfunction.

Objective: A significant proportion of the referrals made to a speech investigation clinic in a cleft unit include patients with non-cleft velopharyngeal dysfunction (VPD). This study aims to quantify the underlying diagnoses of these patients and describe the investigative pathway and diagnostic information subsequent to presentation in our clinic.

Materials And Methods: The case notes of 136 consecutive patients with non-cleft VPD who attended our Velopharyngeal Investigation (VPI) clinic from July 2014-December 2019 were reviewed.

Cigarette smoking as a risk factor for the development of and mortality from hepatocellular carcinoma: An updated systematic review of 81 epidemiological studies.

Background And Aims: Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and its incidence has increased during the past decade. While hepatitis B and C virus infections and alcohol were established risk factors, the impact of smoking on the incidence and mortality of HCC was needed to be confirmed.

Methods: We reviewed cohort and case-control studies evaluating the association between cigarette smoking and incidence and mortality of HCC from MEDLINE and Google Scholar.

Hepatocyte Growth Factor Mediates Enhanced Wound Healing Responses and Resistance to Transforming Growth Factor-β₁-Driven Myofibroblast Differentiation in Oral Mucosal Fibroblasts.

Oral mucosal wounds are characterized by rapid healing with minimal scarring, partly attributable to the "enhanced" wound healing properties of oral mucosal fibroblasts (OMFs). Hepatocyte growth factor (HGF) is a pleiotropic growth factor, with potential key roles in accelerating healing and preventing fibrosis. HGF can exist as full-length or truncated (HGF-NK), NK1 and NK2 isoforms.

A systematic review of the use of lasers for the treatment of hidradenitis suppurativa.

Aim: To conduct a systematic review of the effectiveness of various types of lasers (and light based therapies) for the treatment of hidradenitis suppurativa (HS) and to establish recommendations based on our findings.

Data Sources: MEDLINE, Cochrane and PubMed databases.

Study Selection: English language studies describing the use of laser for the treatment of HS.

Clinical applications of dynamic infrared thermography in plastic surgery: a systematic review.

Background: Infrared thermography (IRT) has become an increasingly utilized adjunct to more expensive and/or invasive investigations in a range of surgical fields, no more so than in plastic surgery. The combination of functional assessment, flow characteristics and anatomical localization has led to increasing applications of this technology. This article aims to perform a systematic review of the clinical applications of IRT in plastic surgery.

Laser ablation and cryotherapy of melanoma metastases.

Both laser therapy and cryotherapy have been used with good results in the ablation of cutaneous melanoma metastases. There is less literature evidence in support of cryotherapy. Carbon dioxide laser therapy is a simple, low cost, patient-friendly technique, effective for palliation of individual lesions.

An algorithmic approach to perineal reconstruction after cancer resection--experience from two international centers.

Aim: This paper aims to simplify the approach to reconstruction of the perineum after resection of malignancies of the anal canal, lower rectum, vulva, and vagina.

Materials And Methods: The data were collected from 2 centers, namely, Addenbrooke's Hospital, University of Cambridge, United Kingdom and Christchurch Hospital, University of Otago, New Zealand. All patients who underwent perineal reconstruction from 1997 to 2009 at Christchurch Hospital (13 years) and 2001 to 2009 at Addenbrooke's Hospital (9 years) were included.

Segmented motion compensation for complementary coded ultrasonic imaging.

Ultrasonic imaging using complementary coded pulses offers the SNR improvements of signal coding without the filter side-lobes introduced by single-transmit codes. Tissue motion between coded pulse emissions, however, can introduce high side-lobes caused by misalignment of complementary filter outputs. This paper presents a method for filtering and motion compensation of complementary coded signals appropriate for use in medical imaging.

Perspectives in the selection of hyaluronic acid fillers for facial wrinkles and aging skin.

Aesthetic surgery is, in the USA at least, no longer a taboo subject. Outside North America, public acceptance continues to grow as more procedures are performed each year. While there appears, anecdotally, to be a decrease in patients undergoing cosmetic treatments because of the global financial crisis, the overall trend remains upward.

Nonchoroidal intraorbital malignant melanoma arising from naevus of Ota.

A case report of nonchoroidal intraorbital malignant melanoma arising from naevus of Ota, in a Caucasian female.