Publications by authors named "Hannah Jeanguenat"
Front Immunol
November 2024
Article Synopsis
- Schistosomes are skilled at evading human immunity, particularly the complement system, allowing them to survive in human blood for years; this study explores how they interact with this immune response.
- The research shows that newly formed schistosomula are initially very vulnerable to complement attack, but they can rapidly boost their survival rate, especially when they recruit complement regulator factor H to avoid destruction.
- The use of the drug praziquantel increases the susceptibility of schistosomula to complement-mediated killing, suggesting that further investigation into factor H's role could help develop new treatments against schistosomes.
