Impact of Red Beetroot Juice on Vascular Endothelial Function and Cardiometabolic Responses to a High-Fat Meal in Middle-Aged/Older Adults with Overweight and Obesity: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial.

Background: High-fat meal (HFM) consumption may induce transient postprandial atherogenic responses, including impairment of vascular endothelial function, in individuals with overweight/obesity. Red beetroot juice (RBJ) may modulate endothelial function and other measures of cardiometabolic health.

Objective: This study investigated the impact of acute and chronic RBJ consumption, including nitrate-dependent and -independent effects, on postprandial endothelial function and other cardiometabolic responses to a HFM.

Curcumin supplementation and motor-cognitive function in healthy middle-aged and older adults.

Background: Recent studies suggest curcumin is a promising nutraceutical for improving important clinical and physiological markers of healthy aging, including motor and cognitive function.

Objective: To determine if curcumin supplementation improves motor and cognitive function in healthy middle-aged and older adults.

Methods: 39 healthy men and postmenopausal women (45-74 yrs) were randomized to 12 weeks of placebo ( = 19) or curcumin supplementation (2000 mg/day Longvida;  = 20) with motor and cognitive function assessed at week 0 and 12.