Analysis of genetic variants with ischaemic events in UK patients prescribed clopidogrel in primary care: a retrospective cohort study.

Objective: To determine whether loss-of-function (LoF) alleles increase risk of ischaemic stroke and myocardial infarction (MI) in UK primary care patients prescribed clopidogrel.

Design: Retrospective cohort analysis.

Setting: Primary care practices in the UK from January 1999 to September 2017.