Publications by authors named "Hannah Finke"

In daily rheumatology practice, systemic sclerosis is primarily regarded as a potentially life-threatening disease characterized by fibrosis of various organs. Therefore, other manifestations, such as orofacial involvement, are often not of primary concern. Furthermore, due to its rarity, the disease might not be well known by dentists, which contrasts with the increased risk of various problems in the oral cavity.

View Article and Find Full Text PDF

Obstructive sleep apnea (OSA) is caused by temporary partial or complete constriction of the upper airway during sleep which leads to reduced blood oxygen and cardiovascular risks. Main symptoms vary between adults and children leading to misdiagnosis or delayed patient identification. To improve early diagnosis, lateral cephalograms can provide craniofacial measurements associated with a higher risk of OSA.

View Article and Find Full Text PDF

Objective: To evaluate the applicability of transplanted teeth in young patients with craniofacial anomalies.

Design: Observational study.

Setting: Comprehensive Centre for Cleft Palate and Craniofacial Malformations.

View Article and Find Full Text PDF

A decline of immune responses and dynamic modulation of the redox status are observed during aging and are influenced by trace elements such as copper, iodine, iron, manganese, selenium, and zinc. So far, analytical studies have focused mainly on single trace elements. Therefore, we aimed to characterize age-specific profiles of several trace elements simultaneously in serum and organs of adult and old mice.

View Article and Find Full Text PDF

Scope: Trace element (TE) deficiencies often occur accumulated, as nutritional intake is inadequate for several TEs, concurrently. Therefore, the impact of a suboptimal supply of iron, zinc, copper, iodine, and selenium on the TE status, health parameters, epigenetics, and genomic stability in mice are studied.

Methods And Results: Male mice receive reduced or adequate amounts of TEs for 9 weeks.

View Article and Find Full Text PDF

Arsenolipids include a wide range of organic arsenic species that occur naturally in seafood and thereby contribute to human arsenic exposure. Recently arsenic-containing phosphatidylcholines (AsPCs) were identified in caviar, fish, and algae. In this first toxicological assessment of AsPCs, we investigated the stability of both the oxo- and thioxo-form of an AsPC under experimental conditions, and analyzed cell viability, indicators of genotoxicity and biotransformation in human liver cancer cells (HepG2).

View Article and Find Full Text PDF

Aim: The aim of this study was to analyze dental and soft tissue profile development in children with normal occlusions to establish age- and gender-specific reference intervals for German children during their active growth period.

Subjects And Methods: The study group consisted of a sample of 31 untreated Caucasian subjects with normal occlusions. Dental casts were analyzed at four different stages of dentitional development.

View Article and Find Full Text PDF
Article Synopsis
  • Miniscrews are crucial for orthodontic anchorage, but their failure can stem from design, location, and biocompatibility issues.
  • The study analyzed four commercially available TiAl6V4 miniscrews by examining their surface roughness and elemental composition using advanced techniques like SEM and EDX.
  • Results showed minor variations in surface quality and composition, but all tested miniscrews demonstrated high cell viability and were non-cytotoxic, indicating that biocompatibility is not a factor in their failure.
View Article and Find Full Text PDF

Sphingosine 1-phosphate (S1P), a bioactive lipid involved in various physiological processes such as cell proliferation and apoptosis, can be irreversibly cleaved by S1P lyase, yielding phosphoethanolamine and (2)-hexadecenal (2HD). The latter metabolite, an α,β-unsaturated fatty aldehyde, may be susceptible to nucleophilic attack by cellular biomolecules. Hence, we studied whether 2HD forms reaction products with GSH and proteins in vitro.

View Article and Find Full Text PDF