Publications by authors named "Hanna Spielmann"
Article Synopsis
- Inherited deficiency of alpha-1 antitrypsin (AAT) leads to serious conditions like liver failure and early emphysema, prompting investigations into new therapies.
- The study explores using pulmonary transplantation of genetically modified macrophages that produce AAT as a potential treatment for lung issues related to AAT deficiency.
- Experiments show that these modified macrophages successfully integrate into lung tissue, maintain their functionality, and produce human AAT, suggesting a promising approach for future therapies.
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