Publications by authors named "Hanna Rebekka Kleinlein"
J Neural Transm (Vienna)
November 2024
Article Synopsis
- This study examined the connection between two imaging techniques, Quantitative Susceptibility Mapping (QSM) and Transcranial Sonography (TCS), to evaluate iron levels in the substantia nigra of patients with Parkinson's disease (PD).
- Eighteen imaging sessions were conducted on 15 PD patients, revealing strong correlations between nigral iron susceptibility and TCS measurements of echogenicity.
- The findings suggest that increased iron accumulation in the substantia nigra may contribute to the observed echogenicity in PD, with echogenicity likely reflecting stored ferritin-bound iron in microglia.
