- The study investigates PFAPA syndrome, an autoinflammatory disease characterized by periodic fever, mouth sores, throat inflammation, and swollen lymph nodes, focusing on its incidence and clinical features in children from western Sweden between 2006 and 2017.
- Researchers analyzed medical records of 336 diagnosed children, finding that most (90%) showed symptoms before age 5, with pharyngitis being the most common symptom, and a minor percentage displaying atypical features like skin rash.
- The estimated annual incidence was 0.86 cases per 10,000 children under 18, and 2.6 cases per 10,000 for those under 5, enhancing the understanding of PFAPA's epidemiology in different age