Publications by authors named "Hanna Ellmann"
Article Synopsis
- This study focused on understanding how monosodium urate crystal deposits affect bone structure in the first metatarsophalangeal joint of patients with tophaceous gout.
- Twenty patients underwent advanced imaging techniques to identify tophi and measure bone erosion and osteophyte formation, with data compared to healthy controls.
- Results showed significant increases in both bone erosions and osteophytes in gout patients, with a direct correlation between the volume of tophi and the degree of bone damage.
Objective: Few studies have systematically and quantitatively addressed the impact of urate-lowering therapy on monosodium urate (MSU) deposits. This study was undertaken to analyze the effect of lifestyle measures and conventional urate-lowering therapy on MSU deposits in patients with gout.
Methods: In this prospective study, subjects with gout according to the American College of Rheumatology/European League Against Rheumatism classification criteria and presence of MSU deposits seen on dual-energy computed tomography (DECT) scans received either lifestyle intervention or conventional urate-lowering therapy for a mean period of 18 months before a follow-up DECT scan.