Publications by authors named "Hanna Deguchi"
We report here two patients exhibiting a combination of falsely elevated serum levels of free thyroxine (FT4), free triiodothyronine (FT3), and thyrotropin receptor antibodies (TRAb), measured using Elecsys assay kits (Roche Diagnostics GmbH). The first patient was a 74-year-old man misdiagnosed with Graves' disease and treated with methimazole. The second patient was a 48-year-old woman whose serum FT4 and FT3 concentrations were found to be high during a blood test.
View Article and Find Full Text PDFContext: Mild autonomous cortisol secretion (ACS) is associated with an increased risk of vertebral fractures (VFx). However, the influence of this condition on bone turnover or its association with mild ACS is still controversial.
Objective: This study aimed to evaluate the impact of mild ACS on bone quality among patients living with the disease.
Article Synopsis
- * This study compared a more cost-effective and quicker immunoassay method for measuring 12 steroid metabolites in serum against traditional techniques like LC-MS/MS and GC-MS, helping to distinguish between cortisol-producing ACC and cortisol-producing adenomas (CPA).
- * Results showed significant increases in steroid metabolites in cortisol-producing ACC compared to CPA, with certain metabolites like 17-hydroxypregnenolone and 11-deoxycorticosterone demonstrating high accuracy and correlation with prognostic