Publications by authors named "Hanlin Shen"

Article Synopsis
  • - The study developed the Parents' Health Literacy Scale on Preventing Road Traffic Injuries (PHLS-PRTIs) to assess how well parents understand safety measures for their children in traffic, given that road traffic injuries are a leading cause of death in kids.
  • - It included a detailed process that involved defining the scale, creating its components, and validating its effectiveness, with a total of 685 parents participating in the development and validation phases.
  • - The resulting scale encompasses five key areas related to health literacy (access, understanding, belief, communication, and usage) and has demonstrated strong reliability and validity, making it a useful tool for healthcare providers to improve parent education around child road safety.
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Municipal solid waste incineration (MSWI) fly ash is a hazardous waste containing heavy metals. Secondary aluminum dross (SAD) is a hazardous waste discharged from aluminum smelting, containing active aluminum nitride (AlN). In this work, heavy metals from MSWI fly ash were reduced into alloy by AlN from SAD, and the slag was manufactured into transparent glass for building.

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Amino acids provide novel and superior performance for two-dimensional materials and bio-based devices. The interaction and adsorption of amino acid molecules on substrates have thus attracted extensive research for exploring the driving forces involved in the formation of nanostructures. Nevertheless, the interactions within amino acid molecules on inert surfaces have not been fully understood.

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Safety and efficient dispose of municipal solid waste incineration (MSWI) fly ash with high toxicity has emerged as a worldwide challenge. Vitrification provides the advantages of capacity reduction, detoxification, and solidification of heavy metals, which has the potential to dispose of hazardous waste on a large scale. Herein, co-vitrification of MSWI fly ash and bottom slag has been accomplished based on the characteristics of calcium and silicon composition.

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Based on STM imaging and DFT calculations, we show the real-space experimental evidence of the interconversion between G-quartets and G-triads on the Au(111) surface, and further reveal the relative stabilities of these two elementary motifs, which helps to increase the fundamental understanding of the relationship between G-triplex and G-quadruplex DNA structures.

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Secondary aluminum dross (SAD) from aluminum industry is classified as a hazardous solid waste due to containing aluminum nitride (AlN). In this work, AlN was first used to reduce heavy metals by pyrometallurgy. The reduction rates for iron, chromium and nickel were up to 90%, 80% and 100%, respectively.

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Secondary aluminum dross (SAD) is solid waste of primary aluminum dross extracted aluminum, which contains approximately 40-60 wt% alumina, 10-30 wt% aluminum nitride (AlN), 5-15 wt% salts and other components. The salts include sodium chloride, potassium chloride and fluorine salts. SAD has dual attributes as resource and pollutant.

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A series of Mn-based catalysts were prepared by a wet impregnation method for the selective catalytic reduction (SCR) of NO with NH. The Mn/Ti-Zr catalyst had more surface area, Lewis acid sites, and Mn on its surface, and showed excellent activity and high N selectivity in a wide temperature range. NH and NO oxidation was investigated to gain insight into NO reduction and NO formation.

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To find the novel hypolipidemic agents, the effects of ursolic acid and artesunate on hyperlipidemia were determined in rats fed a Western-type diet developed a hyperlipidemia. Rats received ursolic acid (50 mg/kg) or artesunate (50 mg/kg) alone, or in combination (25 ± 25 mg/kg and 50 ± 50 mg/kg), to prevent hyperlipidemia. Ursolic acid or artesunate alone significantly decreased the plasma triglyceride, but had no effect on the levels of cholesterol.

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The APP/PS1 mouse model of Alzheimer's disease (AD) exhibits remarkable elevation of β-amyloid production associated with certain behavioral abnormalities, while the senescence accelerated mouse prone 8 (SAMP8) is characterized by early and age-related deterioration of learning and memory. In order to obtain an AD model that develops earlier pathological changes and cognitive impairment, we generated SAMP8-APP/PS1, a novel senescence accelerated APP/PS1 transgenic mouse model of AD. Standard histological staining and immunohistochemistry using an amyloid beta (Aβ) antibody showed an age, genotype and strain-dependent progression of amyloid deposition and neuron loss in the cerebral cortex and hippocampus of SAMP8-APP/PS1 mice.

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Alzheimer's disease (AD) is characterized by a deficit in motor and spatial learning-memory and alteration of non-cognitive behavior. The generation of transgenic mice with presence of AD pathologies that cause learning and memory deficits has led to improved understanding of the behavioral and pathophysiological processes underlying AD. A novel APP/PS1 mouse model in the senescence accelerated mouse prone 8 (SAMP8) background--SAMP8 APP/PS1 was generated.

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Neural stem/progenitor cells (NSPCs) of the subgranular zone have been implicated in cognitive processes, which represent a potentially important source of regenerative medicine for the treatment of neurodegenerative diseases such as Alzheimer's disease (AD). In our previous studies, ZY-1, a novel nicotinic analog, improved cognitive function in transgenic mice model of AD. However, the effect of ZY-1 on the NSPCs remains unclear.

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Alzheimer's disease (AD) is a neurodegenerative disorder marked by progressive loss of memory and cognitive function. One of the new approaches for treating AD is direct stimulation of nicotinic acetylcholine receptors (nAChRs) in the brain. α4β2-nAChR agonists have shown promising potential in preclinical cognition models of AD.

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Two novel homogeneous polysaccharides, APS-1a and APS-3a were successfully isolated from the root of Angelica sinensis. APS-1a was composed of galactose, arabinose and glucose in a relatively molar percentage of 57.34%, 27.

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