Publications by authors named "Hank A Lockman"
Article Synopsis
- - The study investigates the role of Vgamma2Vdelta2 T effector cells in protecting against lung infections, specifically after treatment with HMBPP and IL-2.
- - After administration of HMBPP/IL-2 following Yersinia pestis infection, there was significant growth of Vgamma2Vdelta2 T cells, but they didn’t effectively control the bacterial infection itself.
- - Despite the lack of infection control, the increased Vgamma2Vdelta2 T cells helped reduce lung damage and promote healing by producing FGF-7, demonstrating their potential role in protecting lung tissue during infections.
Cell extracts from Yersinia pseudotuberculosis induced multinucleation in HEp-2 cells in a manner similar to the effect caused by Escherichia coli cytotoxic necrotizing factor (CNF). The activity was not dependent on the Yersinia 70-kb virulence plasmid, and the activity was not inhibited by antibodies capable of neutralizing E. coli CNF type 1.
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