Metal-organic framework-801@MXene nanocomposites as a coating for headspace solid-phase microextraction of methadone and tramadol from biological samples via gas chromatography-mass spectrometry.

MOF-801@MXene nanocomposites are introduced as a new solid-phase microextraction coating. This structure was easily prepared by one-pot solvothermal route. The MOF-801@MXene, MOF-801, and MXene were characterized by various analysis techniques such as field emission scanning electron microscopy, Fourier transform infrared spectroscopy, thermogravimetric analysis, X-ray powder diffraction, and Brunauer-Emmett-Teller.

Molecularly imprinted polypyrrole@CuO nanocomposite as an in-tube solid-phase microextraction coating for selective extraction of carbamazepine from biological samples.

A nanocomposite of molecularly imprinted polypyrrole on copper oxide (MIP@CuO) was introduced as a new coating for in-tube solid-phase microextraction (IT-SPME). The method coupled with HPLC-UV was successfully applied for analysis of carbamazepine (anticonvulsant and bipolar disorder medication) in biological samples. First, in order to increase the surface area and stability of the coating, copper oxide (CuO) nanosheets were synthesized on the inner surface of a copper tube using a chemical method.