Publications by authors named "Hanie Karimi"

The coronavirus disease 2019 (COVID-19) pandemic has disrupted polio immunization programs worldwide. The consequences of these programs' suspension were not fully presented during the COVID-19 pandemic, as some take time to present in a population. We conducted a narrative review to provide a perspective of current literature on the effect of the COVID-19 pandemic on efforts made for poliomyelitis eradication.

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Background: Traumatic brain injury (TBI) is a major cause of global mortality and disability, leading to primary and secondary brain injuries that can result in severe neurological, cognitive, and psychological impairments. Accurate and early prognosis of TBI outcomes is critical, particularly in assessing the risk of neurological decline, intracranial pressure (ICP) changes, and mortality.

Objective: This systematic review aims to evaluate the prognostic value of quantitative pupillometry, particularly the Neurological Pupil Index (NPi), in predicting long-term outcomes in TBI patients.

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Unlabelled: There is presently no disease-modifying therapy for Alzheimer's Disease (AD), which is the most prevalent cause of dementia.

Objective: This study aspires to estimate the efficacy and safety of cell-based treatments in AD.

Methods: Observing the Joanna Briggs Institute (JBI) methods and Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, a systematic search was accomplished in PubMed, Medical Literature Analysis and Retrieval System Online (Medline, via Ovid), Embase; Cochrane, and Cumulative Index of Nursing and Allied Health Literature - CINAHL (via EBSCO) databases up to June 2023.

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  • The study investigates the relationship between cognitive functions and the brain's white matter structure using advanced imaging techniques, specifically Diffusion Magnetic Resonance Imaging (DMRI).
  • Researchers analyzed data from 125 healthy participants, correlating white matter integrity (measured via Quantitative Anisotropy) with scores on various cognitive tests assessing attention, executive function, episodic memory, and working memory.
  • Significant correlations were found, indicating that the integrity of specific white matter tracts is closely linked to cognitive performance, which could aid in the early detection and intervention for cognitive disorders.
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  • * It emphasizes the effectiveness of convolutional neural networks (CNNs) in tumor segmentation, highlighting their clinical applications in treatment planning and monitoring tumor changes.
  • * The study also addresses the evolution of DL models, current challenges like data quality and model interpretability, and suggests future research directions that include tumor heterogeneity and genomic data integration.
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Preparatory brain activity is a cornerstone of proactive cognitive control, a top-down process optimizing attention, perception, and inhibition, fostering cognitive flexibility and adaptive attention control in the human brain. In this study, we proposed a neuroimaging-informed convolutional neural network model to predict cognitive control performance from the baseline pre-stimulus preparatory electrophysiological activity of core cognitive control regions. Particularly, combined with perturbation-based occlusion sensitivity analysis, we pinpointed regions with the most predictive preparatory activity for proactive cognitive control.

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To investigate the response to antidepressants while controlling for sex, which has been controversial, 92 outpatient males and females with major depressive disorder were assigned to sertraline (100 mg/day) or citalopram (40 mg/day) in two strata and were assessed using Hamilton depression rating scale (HDRS) scores and brain-derived neurotrophic factor (BDNF), interleukin (IL)-6 and cortisol serum levels in this 8-week, randomized, parallel-group, double-blind clinical trial. Data of 40 sertraline and 40 citalopram recipients with equal representation of males and females assigned to each medication were analyzed, while their baseline characteristics were not statistically different (P > 0.05).

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  • - This study examined the impact of lead exposure in Iran from 1990 to 2019, measuring factors like deaths and disability-adjusted life years (DALYs) using data from the Global Burden of Disease study.
  • - The results showed a significant decrease in lead exposure-related health issues, with reductions of 50.7% in years of life lost (YLLs) and 48.9% in DALYs, but the overall burden remains high, particularly in low-income areas and for older males.
  • - Key health problems linked to lead exposure include mental disorders and chronic diseases like cardiovascular diseases (CVDs) and chronic kidney diseases (CKDs), with CVDs causing the most significant burden in
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  • REM sleep deprivation (REM SD) in female rats resulted in manic-like behaviors, including increased activity and decreased anxiety and depressive behaviors.
  • The study examined the effects of crocin, a compound from saffron, as a potential treatment to counteract behavioral changes caused by REM SD.
  • Results indicated that crocin at various doses could partially or fully reverse the negative behavioral effects of REM SD, suggesting it may be a useful therapeutic option.
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Background: Cognitive impairment is highly prevalent in multiple sclerosis (MS) with poorly understood underlying mechanisms. Lipids are considered to be associated with MS progression through the inflammatory and oxidative stress pathways, brain atrophy, cellular signaling, and tissue physiology. In addition, serum lipids are proposed as a modifiable factor affecting the neuropsychiatric condition; therefore, this study aims to assess the association between serum lipid levels and cognitive outcomes in MS.

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  • * Lithium treatment at doses of 50 and 100 mg/kg effectively mitigated these manic-like effects, with the higher dose also increasing levels of brain-derived neurotrophic factor (BDNF).
  • * The study proposes that chronic REM SD can create a rodent model for mania, highlighting the need for further research on behavioral changes related to REM SD in both male and female rats.
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Introduction: Autism spectrum disorder (ASD) is an early-onset disorder with a prevalence of 1% among children and reported disability-adjusted life years of 4.31 million. Irritability is a challenging behavior associated with ASD, for which medication development has lagged.

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Multiple sclerosis (MS) is a chronic immune-mediated demyelinating disease of the central nervous system. Selenium is a trace element with significant antioxidant activity. This study aimed to seek evidence concerning selenium supplementation in MS.

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  • * Quantum dots (QDs), a type of engineered nanoparticle, are highlighted as promising tools for gene delivery, particularly to retinal cells, due to their unique properties such as photoluminescence and biocompatibility.
  • * The study reviews the criteria for using QDs in gene delivery, including their physical and chemical traits, and presents findings that support their potential in biomedical applications like biosensing and drug delivery.
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Since 2020, the highly contagious nature and various transmission routes of SARS-CoV-2 have rendered the pandemic interminable. Vertical transmission (VT) through the placenta and breast milk, which is frequent for certain virus types, is thought to exist for SARS-CoV-2 and is hypothesized by many researchers. Conversely, antibodies are produced to counteract the effect of viruses.

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Key Clinical Message: This case emphasizes the significance of cardiac amyloidosis as a potential diagnosis in individuals manifesting with lesion-free pruritus and normal liver tests.

Abstract: Amyloidosis is a complex disorder in which misfolded proteins accumulate in various organs of the body. Cardiac amyloidosis (CA) can lead to heart failure, cardiac arrhythmia, sudden cardiac death, and deposition of proteins in coronary arteries.

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Introduction: Acute myeloid leukemia is a rare event in post-liver-transplantation recipients. In the present report, we described a case of extramedullary acute myeloid leukemia, M/M subtype, following orthotopic liver transplant.

Case Presentation: The patient was a 50-year-old Iranian woman who underwent orthotopic liver transplant due to hepatitis B-related cirrhosis (Child C, MELD (model for end-stage liver disease score) = 22).

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  • Estimating health loss trends in Peru from 1990 to 2019 is crucial for improving healthcare resource allocation and system performance, using data from the Global Burden of Disease study.
  • The Peruvian population rose to 33.9 million by 2019, with life expectancy at birth increasing from 69.2 to 80.3 years, largely due to a decrease in under-5 mortality and infectious diseases, while disability-adjusted life-years (DALYs) showed a decline in overall health burden.
  • There was a notable shift towards non-communicable diseases as the leading cause of health loss, with major contributors to DALYs in 2019 including neonatal disorders, lower respiratory infections, and lifestyle
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Introduction: Diabetic retinopathy (DR) is one of the most threatening complications of diabetes and a leading cause of visual loss in working-age population. Although exercise is beneficial in diabetes, previous studies have showed contradictory and inconclusive results on how it effects DR. In this study, we aimed to investigate the effect of moderate-intensity aerobic exercise on non-proliferative diabetic retinopathy.

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Transcranial magnetic stimulation (TMS) has become a promising strategy for bipolar disorder (BD). This study reviews neuroimaging findings, indicating functional, structural, and metabolic brain changes associated with TMS in BD. Web of Science, Embase, Medline, and Google Scholar were searched without any restrictions for studies investigating neuroimaging biomarkers, through structural magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), functional MRI (fMRI), magnetic resonance spectroscopy (MRS), positron emission tomography (PET), and single photon emission computed tomography (SPECT), in association with response to TMS in patients with BD.

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Key Clinical Message: This case report emphasizes that we should analyze a patient's signs and symptoms as a whole rather than relying exclusively on a common pattern to diagnose the condition and indicates that thorough histological investigation and sample collection are needed to accurately diagnose this malignancy.

Abstract: Angiosarcoma is a rare, fatal, and poorly understood malignant tumor of vascular endothelial cells which is a challenging disease to diagnose in the clinical settings and requires early diagnosis to achieve a favorable prognosis. Paraneoplastic syndromes associated with angiosarcoma can include hypercoagulability, thrombocytopenia, anemia, fever, weight loss, and night sweats.

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Introduction: SARS-CoV-2 causes more severe symptoms in most chronic diseases, and rheumatic disease is no exception. This study aims to investigate whether there is an association between the use of immunomodulatory medications, including conventional disease-modifying agents (csDMARDs), glucocorticoids, and biologic DMARDs, and outcomes such as hospitalization and lung involvement in patients with rheumatic disease with COVID-19.

Methods: We performed a cross-sectional study on 177 COVID-19 cases with rheumatologic diseases using immunomodulatory drugs as their regular treatment.

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