With the exacerbated urban heat island effect, urban populations are exposing to high temperatures and increased exposure to particulate matter (PM) during daily commutes (especially vulnerable groups). Under high-temperature urban environments, the traffic emissions and the individual respiratory rate would rise simultaneously, causing an elevated risk of air particulate exposure. Most previous studies on PM at bus stations have focused on concentration levels, while neglecting chemical analyses of metal elements or increased human respiratory intake in high-temperature environments.
View Article and Find Full Text PDFDue to the outbreak of COVID-19, an increased risk of airborne transmission has been experienced in buildings, particularly in confined public places. The need for ventilation as a means of infection prevention has become more pronounced given that some basic precautions (like wearing masks) are no longer mandatory. However, ventilating the space as a whole (e.
View Article and Find Full Text PDFBackground: Mounting evidence indicates that stem cell-derived exosomal miRNAs have therapeutic effects on traumatic brain injury (TBI). This research is focused on exploring the molecular processes of miR-124-3p obtained from bone marrow stromal cells-derived exosomes (BMSCs-Exos) in attenuating posttraumatic glutamate-mediated excitotoxicity.
Methods: We created a TBI rat model and analyzed the expression profile of miRNA through miRNA microarray.
Oral squamous cell carcinoma (OSCC) is a common malignant tumor of the oral cavity. Shelterin complex gene (SG) has an important role in regulating telomere structure and length. SG is considered promising as a novel prognostic marker for cancer and a potential target for tumor therapy.
View Article and Find Full Text PDFChronic myeloid leukemia (CML) is a malignant myeloproliferative tumor. 2-Methoxyestradiol (2-ME) is an endogenous estrogen metabolite that shows efficacy in human malignancies. Ascorbic acid (AA) possesses antioxidant activity.
View Article and Find Full Text PDFBackground: Gastrointestinal mucormycosis (GIM) is a rare, opportunistic fungal infection with poor prognosis. Clinically, it is difficult to diagnose GIM owing to its nonspecific clinical symptoms and poor suspicion. The estimated incidence of GIM is inaccurate, and most cases are diagnosed accidentally during surgery or upon postmortem examination.
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