Publications by authors named "Hanhui Yang"
Article Synopsis
- Breast cancer is a major health issue in women and is associated with metabolic dysfunction, particularly related to mitochondrial metabolism, but the impact of mitochondrial metabolism-related genes (MMRGs) on breast cancer prognosis is not fully understood.
- Researchers developed a risk score model using MMRGs from various databases and found that a 12-gene model could predict patient survival and was an independent factor alongside traditional clinical metrics.
- Analysis showed that patients categorized as low-risk had better immune responses and were more sensitive to specific anti-tumor drugs, indicating that understanding MMRG characteristics can enhance treatment strategies and prognostic predictions for breast cancer patients.
Article Synopsis
- Gastric cancer is a prevalent type of cancer with high rates of both incidence and death, and the study focuses on the role of microRNA, specifically miR‑204‑5p, in this disease.
- The research found that miR‑204‑5p is downregulated in gastric cancer cells, and its overexpression can significantly reduce cell proliferation, migration, and invasion, while increasing apoptosis in these cells.
- miR‑204‑5p was shown to directly target the HER‑2 gene, suggesting that it could serve as a potential therapeutic target for treating gastric cancer by promoting anti-tumor effects.
