Successful surgical treatment of the supradiaphragmatic middle aortic syndrome by an extra-anatomical bypass in a child.

We report a 5-year-old girl (13kg) was referred to our facility for cardiologic examination due to uncontrolled hypertension and significant heart failure. Chest radiography elevated cardiothoracic ratio of over 60% with rib notching and the absence of an aortic knob. Transthoracic echocardiography showed a dilated left ventricle with a reduced ejection fraction and significant stenosis of the descending aorta with a pressure gradient of 64 mm Hg.

Isolation of a 177Hf complex formed by beta-decay of a 177Lu-labeled radiotherapeutic compound and NMR structural elucidation of the ligand and its Lu and Hf complexes.

(177)Lu-AMBA (AMBA = DO3A-CH(2)CO-G-[4-aminobenzoyl]-QWAVGHLM-NH(2)) is being developed for the radiotherapeutic treatment of tumors that express the gastrin-releasing peptide receptor (GRP-R). In this study we investigated the fate of the (177)hafnium ((177)Hf) that forms upon the decay of (177)Lu while the latter is complexed with AMBA. When decayed solutions of (177)Lu-AMBA were analyzed, it was found that (177)Hf is retained in the DO3A monoamide chelator, forming a pair of interconverting isomers.