Publications by authors named "Hangzhou Wang"

Article Synopsis
  • T2 hyperintensities (T2Hs) on MRI scans in children with neurofibromatosis type 1 (NF1) are important for identifying brain abnormalities and distinguishing lesions that require oncologic surveillance.
  • A study evaluated 98 NF1 patients' brain MRIs and found T2Hs present in 62.2% of them, proving to be sensitive and specific markers for NF1 diagnosis.
  • The T2Hs were classified into low-risk, medium-risk, and high-risk tumor lesions, with high-risk lesions leading to surgical treatment; results indicated that low and medium-risk lesions did not progress to high-risk status during follow-up.
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Article Synopsis
  • A study was conducted to examine changes in the incidence of brain abscesses in children before and after the COVID-19 pandemic, revealing a significant increase in cases post-pandemic.
  • The data indicated an increase from an average of 2.4 cases per year pre-pandemic to 5.5 cases per year post-pandemic, with higher rates of fever and ICU admissions noted among patients.
  • The findings emphasize the importance of vaccination against streptococcal infections, which were the leading cause of brain abscesses in both time periods studied.
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Objective: The link between tethered cord syndrome (TCS) and neurofibromatosis type 1 (NF1) remains unclear. To date, only 2 studies have indicated a high occurrence of TCS in the pediatric NF1 patient population. Our study aims to ascertain the incidence of TCS among Chinese pediatric patients with NF1.

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Objective: Acute rupture and hemorrhage of pediatric brain arteriovenous malformations (AVMs) may lead to cerebral herniation or intractable intracranial hypertension, necessitating emerging surgical interventions to alleviate intracranial pressure. However, there is still controversy regarding the timing of treatment for ruptured AVMs. This study aimed to assess the feasibility of utilizing three-pillar expansive craniotomy (3PEC) at different times during the treatment of pediatric ruptured supratentorial AVMs.

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A waterborne polyurethane pressure-sensitive adhesive (WPUPSA) has the advantages of low pollution and good viscoelasticity. However, its poor thermo-tolerance limits its application in the field of high temperatures. Hence, a novel silicone-modified strong thermo-tolerant waterborne polyurethane/polyimide pressure-sensitive adhesive is developed as a way to remedy this problem.

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Purpose: Lateral meningocele syndrome (LMS) is a rare genetic connective tissue disorder which is associated with meningocele-related neurologic dysfunction. Several patients with LMS have been reported. But, guidelines for screening and treatment of LMS have not been established.

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Unlabelled: The variation of and the interrelation between different energy markets significantly affect the competitiveness of various energy technologies, therefore complicate the decision-making problem for a complex energy system consisting of multiple competing technologies, especially in a long-term time frame. The interrelations between these markets have not been accounted for in the existing energy system modelling efforts, leading to a distortion of understanding of the market impact on the technological choices and operations in the real world. This study investigates the strategic and operational decision-making problem for such an energy system characterized by three competing technologies from crude oil, natural gas, and coal.

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Purpose: The aim of this study is to conduct a retrospective review of data obtained in all consecutive patients who had undergone cerebral decompression using the 3-pillar expansive craniotomy (3PEC) in our hospital between 2016 and 2020.

Methods And Results: We developed a novel craniotomy technique using expansion cranioplasty in patients with traumatic brain injury or stroke, which could relieve intracranial hypertension, maintain cerebral protection, and avoid subsequent cranial repair. Sixteen patients aged 2-18 years old underwent the 3PEC.

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Purpose: Chiari I malformation (CIM) is a common pediatric neurologic anomaly which could be associated with a variety of genetic disorders. However, it is not always clear whether the observed associations between CIM and RASopathies are real or random. The knowledge of the real association could provide useful guidance to clinicians.

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Tumor driver genes are genes where structural or sequence mutations confer a selective advantage for cancer cells. The individualized targeting of tumor driver genes has become a topic of interest for tumor treatment. The prognosis for medulloblastoma (MB), a common type of malignant intracranial tumor found in children, is poor.

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Mapping small-scale high-precision velocity fields is of great significance to oceanic environment research. Coastal acoustic tomography (CAT) is a frontier technology used to observe large-scale velocity field in the horizontal slice. Nonetheless, it is difficult to observe the velocity field using the CAT in small-scale areas, specifically where the flow field is complex such as ocean ranch and artificial upwelling areas.

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Microplastic pollution in aquatic environment has raised concern and as a result a number of studies have recently been published to find solutions for its rapid increase. Different methods have been proposed for microplastic identification. Spectral imaging shows a lot of promise for polymer identification; however, the identification time needs to be improved.

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Purpose: The acquired Chiari type I malformation is a rare late complication of supratentorial shunting in children which is often accompanied by abnormal cranial vault thickening. Several surgical treatments for this disease have been proposed including supratentorial skull enlarging procedures and subtentorial craniotomy. But there is still debate about the best treatment strategy for this disease.

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This paper investigated the use of spectra and multispectral images for on-site visualized classification of transparent hazards and noxious substances (HNS), such as benzene, xylene, and palm oil, floating on a water surface with the potential use for rapid classification of multiple HNS during a leak accident. Partial least-squares discrimination analysis (PLS-DA) and least-squares support vector machine (LS-SVM) models achieved a classification accuracy of 100% for spectral reflectance (325-900 nm) and multispectral image at nine wavelengths. Wavelength division and selection were applied for spectra and spectral images, respectively, to reduce the difficulty in data collection and to simplify the redundant bands.

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ᅟJaffe-Campanacci is a rare syndrome characterised by axillary freckles, multiple non-ossifying fibromas of the long bones and jaw, and café-au-lait spots, associated with some features of neurofibromatosis type 1 (NF1). Cherix et al. and Colby and Saul suggested that Jaffe-Campanacci syndrome (JCS) might be a distinct form of NF1.

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Survivin is a tumor-associated gene, which has been detected in a wide variety of human tumors. Previous research has shown that Survivin can affect hepatoma carcinoma cell radiosensitivity. However, little is known about the role of Survivin in ionizing radiation resistance in glioma cells.

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Adaptive measurement is a major concern when using miniature spectrometers in extreme environments, especially when the ambient temperatures and incident light intensities vary greatly. In this study, parameters, including the signal output and the relevant noise and signal-to-noise ratio (SNR) of a fiber optic spectrometry system composed of a photodiode array miniature spectrometer and external driver electronics were examined at multiple integration times from -50°C to 30°C, well below the specified operating temperature of this spectrometer. The relationships between those parameters and incident light level were also examined, at a single temperature of 0°C.

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Glioma is one of the most common types of adult primary brain tumors, and the underlying molecular mechanisms still remain unclear. Nuclear factor-kappa B1 (NF-κB1) is involved in a variety of malignancies and is widely expressed in malignant tumors. However, the expression of NF-κB1 in different grades of glioma, the correlation between NF-κB1 and Bcl-2 expressions in gliomas, and the research between NF-κB1 and early apoptosis of glioma cells have not been reported so far.

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Underwater spectral imaging is a promising method for mapping, classification and health monitoring of coral reefs and seafloor inhabitants. However, the spectrum of light is distorted during the underwater imaging process due to wavelength-dependent attenuation by the water. This paper presents a model-based method that accurately restores brightness of underwater spectral images captured with narrowband filters.

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Turbidity measurement is important for water quality assessment, food safety, medicine, ocean monitoring, etc. In this paper, a method that accurately estimates the turbidity over a wide range is proposed, where the turbidity of the sample is represented as a weighted ratio of the scattered light intensities at a series of angles. An improvement in the accuracy is achieved by expanding the structure of the ratio function, thus adding more flexibility to the turbidity-intensity fitting.

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Gliomas are the most common malignant primary brain tumors, and new clinical biomarkers and therapeutic targets are imminently required. MicroRNAs (miRNAs) are a novel class of small non-coding RNAs (∼22nt) involved in the regulation of various biological processes. Here, by using real-time polymerase chain reaction, miRNA-132 was found to be significantly deregulated in glioma tissues.

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Objective: The aim of this study was to assess the therapeutic effects and complications of tension band wiring (TBW) through the use of double-cannulated screws versus conventional TBW in the treatment of olecranon fractures.

Methods: Eligible participants were randomly assigned to 2 groups to undergo different methods of fixation. The related indices and data of the 2 groups were collected for comparative analysis after an average follow-up of 32.

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In glioma tissues, there are small cell populations with the capability of sustaining tumor formation. These cells are referred to as glioma stem cells (GSCs). However, the presence of subpopulations of GSCs, and the differences between each subpopulation remain to be fully elucidated.

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