Background: Carbapenemase-producing Enterobacteriaceae (CPE) infections lead to considerable morbidity and mortality. We assessed the potential of fecal microbiota transplantation (FMT) to eradicate CPE carriage and aimed to explain failure or success through microbiome analyses.
Methods: In this prospective cohort study, all consenting eligible CPE carriers received oral capsulized FMT for 2 days.
Background: Corticosteroids (CS) therapy to Clostridioides difficile infection (CDI) in inflammatory bowel disease (IBD) flares may worsen CDI outcomes.
Aim: Assess the impact of early CS exposure on outcomes of IBD patients diagnosed with CDI.
Methods: Retrospective study of IBD patients admitted with first-time CDI between 2002 and 2018.
Compositionally complex alloys, or high entropy alloys, are good candidates for applications at higher temperatures in gas turbines. After their introduction, the equiatomic AlCoCrCuFeNi (at.%) served as a starting material and a long optimization road finally led to the recently optimized AlCoCrFeNiTi (at.
View Article and Find Full Text PDFCompositionally complex alloys, also called high entropy alloys, have been investigated for over a decade in view of different applications, but so far only a small number of alloys can be considered as presenting good enough properties for industrial application. The most common family of elements is Al-Co-Cr-Cu-Fe-Ni. The equiatomic alloy having 5 phases and being too brittle, the composition has been modified in order to improve the mechanical properties.
View Article and Find Full Text PDF