Sporotrichoid Primary Cutaneous Nocardiosis: A Rare Case of Isolated Upper-Limb Involvement in a Housewife.

Nocardiosis is a rare infection due to a ubiquitous, gram-positive, weakly acid-fast, filamentous, aerobic bacteria, that are usually responsible for opportunistic infection in immunocompromised patients. Less frequently, nocardiosis can affect immunocompetent patients, causing primary cutaneous infections. Here we present a case of a 45-year-old housewife with a 12-day history of red painful nodules arranged linearly on her right upper limb, without any apparent history of injuries or comorbidities, albeit with a hobby of gardening.

Chronic bullous disease of childhood with IgG predominance: what is the locus standi?

Linear IgA disease (LAD) is an acquired, autoimmune, subepidermal, blistering disease, characterized by linear deposition of IgA along the dermoepidermal junction on immunofluorescence. Some cases known as 'mixed immunobullous disease' show weak staining with other immune reactants like IgG, IgM or C3. We report a rare case of a child having typical manifestations of LAD (chronic bullous disease of childhood), but with IgG predominance rather than IgA.

Fetal varicella syndrome.

Fetal varicella syndrome is a rare condition of the newborn, presenting with cutaneous scars, limb defects and ocular and central nervous system abnormalities. It is due to varicella or zoster developing in the fetus following maternal varicella infection during early pregnancy. We are reporting one such patient who presented with a linear, depressed, erythematous scar over the left forearm and axillary fold, with a history of maternal chicken pox during the first trimester of pregnancy.

A comparative evaluation of skin and nerve histopathology in single skin lesion leprosy.

Background: In spite of leprosy being a disease of nerves, ROM therapy for single skin lesion leprosy was based on clinical trials without much evidence-based studies of nerve pathology. The present study was undertaken to compare the histology of skin and nerve in single skin lesion leprosy, and to assess the scientific rationale and justification of single dose ROM therapy.

Methods: Twenty-seven untreated patients with single skin lesion without significantly thickened peripheral nerves were selected.

Nail changes and disorders among the elderly.

Nail disorders are frequent among the geriatric population. This is due in part to the impaired circulation and in particular, susceptibility of the senile nail to fungal infections, faulty biomechanics, neoplasms, concurrent dermatological or systemic diseases, and related treatments. With aging, the rate of growth, color, contour, surface, thickness, chemical composition and histology of the nail unit change.