Publications by authors named "Hande Alibas"
Background: Ataxia telangiectasia (AT) is a genetic multisystemic disorder affecting the nervous system. Data on neurocognitive functioning in AT are limited and focused on patients at various stages of disease. Because of the genetic nature of the disorder, parents of patients may also display subtle neurological problems.
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- Chronic inflammatory demyelinating polyneuropathy (CIDP) involves myelin-related issues, small fiber neuropathy (SFN), and axonal degeneration, contributing to severe symptoms and reduced quality of life.
- In vivo corneal confocal microscopy (IVCCM) offers a non-invasive method to study small fiber damage in CIDP patients, with 15 patients assessed alongside 32 healthy controls.
- Results revealed significantly lower corneal nerve fiber density and length in CIDP patients, indicating the potential role of IVCCM as a biomarker for understanding and evaluating this condition.
: Obstructive sleep apnea (OSA) is a sleep disorder accompanied by intermittent hypoxia. Neuromuscular transmission (NT) is known to be disturbed under chronic hypoxia. In this descriptive study, it has been aimed to test NT under intermittent hypoxia in OSA.
View Article and Find Full Text PDFExecutive functions in sarcoidosis: a neurocognitive assessment study.
Sarcoidosis Vasc Diffuse Lung Dis
April 2018
Sarcoidosis is a multisystem, inflammatory disease characterized by non-caseating granulomas in multiple organs. Neuropsychological impairment has been told to be present in about 10% of sarcoidosis patients with diagnosed central nervous system (CNS) involvement. Both anatomical lesions and changes in immunological parameters in sarcoidosis may cause cognitive impairment.
View Article and Find Full Text PDFIntroduction: An increased response to painful stimuli without spontaneous pain suggests a role of central hyperexcitability of pain pathways in the pathogenesis of myofascial pain syndrome (MPS). In this study we aimed to test the hypothesis that spinal pain pathways are affected in MPS. We used cutaneous silent period (CSP) parameters to demonstrate the hyperexcitability of spinal pain pathways in MPS.
View Article and Find Full Text PDFExecutive functions in sarcoidosis: a neurocognitive assessment study.
Sarcoidosis Vasc Diffuse Lung Dis
December 2016
Not available.
View Article and Find Full Text PDFPurpose Of The Study: We proposed a new electrophysiological parameter medial plantar (MP)-to-radial amplitude ratio (MPRAR), similar to sural-to-radial amplitude ratio (SRAR), in the diagnosis of distal sensory polyneuropathy (DSP), based on the concept that distal nerves are affected more and earlier than proximal nerves in axonal neuropathies. We aimed to investigate the diagnostic sensitivity of this parameter in diabetic DSP, together with sensitivities of SRAR and MP nerve action potential (NAP) amplitude.
Materials And Methods: In 124 healthy controls and 87 diabetic patients with clinically defined DSP and normal sural responses, we prospectively performed sensory nerve conduction studies (NCS), and evaluated the MP NAP amplitude, MPRAR and SRAR values.