Emergence of Methicillin-Resistant ST239/241 -III Mercury in Eastern Algeria.

In this paper, we investigate the epidemiology of infections-associated () from the Medical Intensive Care Unit (MICU) at University Hospital Center of Constantine (UHCC) in Algeria, with a special emphasis on methicillin-resistant strains (MRSA) revealed by cefoxitin disks (30 μg), then confirmed by penicillin-binding protein (PBP2a) agglutination and real-time polymerase chain reaction (RT-PCR) targeting and C genes. Staphylococcal Cassette Chromosome ( type), staphylococcal protein A (-type), multilocus sequence type (MLST), Panton-Valentine Leucocidin (PVL), and toxic shock syndrome toxin-1 (TSST-1) were further investigated in all isolates, and whole genome sequencing was performed for a selected subset of three hospital-acquired MRSA (HA-MRSA) isolates. A measurement of 80% out of the 50 isolates were identified as HA-MRSA harbouring the gene, and 72.