Sinonasal mucormycosis in immunocompromised pediatric patients.

Objective: Sinonasal mucormycosis is a rare fulminant disorder that typically affects immunocompromised patients. This article focuses primarily on the clinical manifestations and the importance of early diagnosis and treatment of this disease.

Patients And Methods: Four pediatric cases of sinonasal mucormycosis encountered over an 8-year-period in our institution are reported.

Pulmonary hypertension in children and young adults with sickle cell disease: evidence for familial clustering.

Background: Pulmonary hypertension (PHTN) is increasingly recognized as a serious complication of sickle cell disease (SCD). Our objective was to determine the prevalence of PHTN and identify factors associated with PHTN among children and young adults with SCD in Lebanon.

Procedure: From June 2004 to June 2008, 90 patients were studied.

Familial infantile pyknocytosis in association with pulmonary hypertension.

Infantile pyknocytosis is a rare condition characterized by transient neonatal hemolytic anemia associated with increased pyknocyte count on blood smear. We describe three siblings with infantile pyknocytosis, born to consanguineous parents. The first and third siblings had neonatal hemolytic anemia that resolved spontaneously at 6 months.