Publications by authors named "Hanan Smadi"

Article Synopsis
  • Invasive pneumococcal disease (IPD) has been monitored in Canada since 2000, highlighting shifts in serotype distribution due to conjugate vaccines, with a report summarizing data from 2021 and 2022 on demographics, serotypes, and antimicrobial resistance.
  • The National Microbiology Laboratory collaborated with public health labs across Canada, reporting nearly 2,000 isolates in 2021 and nearly 3,800 in 2022, using various methods for serotype determination and susceptibility testing.
  • While IPD cases decreased to 5.62 per 100,000 population in 2021, 2022 saw a rise back to pre-pandemic levels, with notable increases in certain serotypes
View Article and Find Full Text PDF

Background: Invasive group A streptococcal (iGAS, ) disease has been a nationally notifiable disease in Canada since 2000. This report summarizes the demographics, types, and antimicrobial resistance of iGAS isolates collected in Canada in 2021 and 2022.

Methods: The Public Health Agency of Canada's National Microbiology Laboratory collaborates with provincial and territorial public health laboratories to conduct national surveillance of invasive .

View Article and Find Full Text PDF

Background: In October 2020, an investigation began in Canada on an outbreak of Typhimurium infections of the same strain as a concomitant outbreak in the United States (US) that was linked to pet hedgehogs. The objective of this article is to identify the source of the outbreak, determine if there was a link between the Canadian and US outbreaks and identify risk factors for infection to inform public health interventions.

Methods: Cases were identified through whole genome sequencing of Typhimurium isolates.

View Article and Find Full Text PDF
Article Synopsis
  • This study aims to analyze the genetic backgrounds and resistance traits of common pneumococcal serotypes in Canada over the past five years, focusing on their behavior after the introduction of the PCV13 vaccine.
  • Researchers sequenced the genomes of a sample from the ten most prevalent serotypes and used this data to identify important characteristics, including virulence and antimicrobial resistance (AMR) genes.
  • The results revealed significant changes in the prevalence of certain serotypes, with some increasing in numbers and one, 19A, decreasing, highlighting the need for ongoing surveillance to track new bacterial lineages and AMR development in Canada.
View Article and Find Full Text PDF

Background: Invasive pneumococcal disease (IPD), which is caused by , has been a nationally notifiable disease in Canada since 2000. The use of conjugate vaccines has markedly decreased the incidence of IPD in Canada; however, the distribution of serotypes has shifted in favour of non-vaccine types. This report summarizes the demographics, serotypes and antimicrobial resistance of IPD infections in Canada in 2020.

View Article and Find Full Text PDF

Background: Invasive group A streptococcal (iGAS) disease (caused by ) has been a nationally notifiable disease in Canada since 2000. This report summarizes the demographics, types and antimicrobial resistance of iGAS infections in Canada in 2020.

Methods: The Public Health Agency of Canada's National Microbiology Laboratory (Winnipeg, Manitoba) collaborates with provincial and territorial public health laboratories to conduct national surveillance of invasive typing was performed on all isolates using the Centers for Disease Control and Prevention sequencing protocol.

View Article and Find Full Text PDF

Background: The number of invasive group A (iGAS) infections due to hitherto extremely rare type strains has increased in several Canadian provinces since late 2015. We hypothesized that the cases recorded in the different provinces are linked and caused by strains of an clone that recently emerged and expanded explosively.

Methods: We analyzed both active and passive surveillance data for iGAS infections and used whole-genome sequencing to investigate the phylogenetic relationships of the strains responsible for these invasive infections country-wide.

View Article and Find Full Text PDF

Background And Objectives: Saudi Arabia has implemented strategies for the eradication of malaria. However, influx of people from countries endemic for malaria for either employment or Hajj makes the country highly susceptible to malaria importation. The Makkah region is known to host millions of immigrants yearly and has a surveillance system to monitor the incidence of malaria.

View Article and Find Full Text PDF

Setting: National Tuberculosis Program, Department of Public Health, Ministry of Health, Kingdom of Saudi Arabia (KSA).

Objective: To summarize data on the incidence of tuberculosis and associated risk factors for cases reported during 2010-2011.

Design: Retrospective analysis of routinely collected data through an established national disease notification system of the Ministry of Health in KSA.

View Article and Find Full Text PDF

Growth and inactivation regression equations were developed to describe the effects of temperature on Salmonella concentration on chicken meat for refrigerated temperatures (⩽10°C) and for thermal treatment temperatures (55-70°C). The main objectives were: (i) to compare Salmonella growth/inactivation in chicken meat versus laboratory media; (ii) to create regression equations to estimate Salmonella growth in chicken meat that can be used in quantitative risk assessment (QRA) modeling; and (iii) to create regression equations to estimate D-values needed to inactivate Salmonella in chicken meat. A systematic approach was used to identify the articles, critically appraise them, and pool outcomes across studies.

View Article and Find Full Text PDF

The objective was to review the literature related to the risk of salmonellosis from chicken consumed in private homes in Canada. The pathway of concern was retail-to-consumption at private homes due to the direct link between this pathway and public health. A qualitative review was conducted by searching Canadian governmental agencies' webpages, published peer-reviewed journals, and by contacting experts in the field.

View Article and Find Full Text PDF

The current quantitative risk assessment model followed the framework proposed by the Codex Alimentarius to provide an estimate of the risk of human salmonellosis due to consumption of chicken breasts which were bought from Canadian retail stores and prepared in Canadian domestic kitchens. The model simulated the level of Salmonella contamination on chicken breasts throughout the retail-to-table pathway. The model used Canadian input parameter values, where available, to represent risk of salmonellosis.

View Article and Find Full Text PDF