Effect of telerehabilitation assessment for adults with musculoskeletal conditions on access to care beyond the COVID-19 pandemic: A retrospective case-control analysis.

Background: Musculoskeletal (MSK) conditions are the leading cause of disability worldwide. In MSK care, access to physical therapy is a major issue. The effectiveness of telerehabilitation phone assessment in improving access to care for MSK conditions has not yet been established in Saudi Arabia.

Dermatological Manifestation of SLE Patients, Living in Aseer Region.

Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disease that affects both men and women differently and has a variety of multisystemic symptoms. One of the diseases most often affected target organs is the skin. Different ethnic and racial groupings may display variations in disease incidence, clinical heterogeneity, and severity depending on environmental, cultural, or genetic factors.

Pulmonary Manifestations of Systemic Lupus Erythematosus Among Adults in Aseer Region, Saudi Arabia.

Background: Nearly half of the Systemic lupus erythematosus (SLE) patients develop lung involvement. The study assessed the extent of pulmonary involvement among SLE patients and to identify the associated factors in the population.

Methodology: This retrospective cohort study was conducted at Aseer Hospital and Khamis Myshat Hospital in the Southern region of Saudi Arabia.

A case of truncal complex regional pain syndrome: literature review.

Introduction And Importance: Complex regional pain syndrome is a rare and chronic pain disorder characterized by an abnormal level of pain disproportionate to the initiating cause, often manifesting well after the triggering event.

Case Presentation: The authors present a free past medical history 33-year-old female, employed as a nurse in an intensive care unit, presented with a 9-year history of diffuse back pain. Her symptoms initially emerged at the neck with muscle spasms and restricted neck mobility, eventually progressing along the spine.

Correlation between head circumference and mesio-distal width of the maxillary central incisor: a cross sectional study among three different population groups.

The size and shape of a tooth vary between individuals of different ethnic groups and genders because of the influence of different genetic factors. The information regarding the different anatomical factors using maxillary anterior teeth is very scanty. Thus to give more clarity, a study was planned to assess the correlation between head circumference and tooth-mesiodistal width among children of different ethnic origins.

Cardiovascular Complications in Lupus Patients in the Aseer Region, Saudi Arabia.

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease with high morbidity. The objective of this study was to investigate the prevalence and types of cardiovascular complications among patients with SLE in the Aseer region of Saudi Arabia.

Method: This study is retrospective record-based research conducted at Aseer Central Hospital in the Aseer region from 2020 to 2022.

Myopia Progression Among School-Aged Children in the COVID-19 Distance-Learning Era.

Objective: To investigate the effect of online learning and other environmental factors on myopia progression during the Coronavirus pandemic (COVID-19).

Methods: A retrospective cohort study from 2018 to 2021. Data from children aged 6-14 were gathered during three visits: pre-pandemic, at the beginning, and during the pandemic.

Measuring empathy in medical students: A cross-sectional study.

Objective: To measure the empathy levels of undergraduate medical students, and to explore whether the empathy level has any significant association with gender, academic year and academic achievement.

Methods: The cross-sectional study was conducted at the College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia, from January to March 2020, and comprised medical students. Data was collected using the pre-validated student version of the Jefferson Scale of Empathy.

Patterns of Response to Different Treatment Strategies in Seropositive Rheumatoid Arthritis Patients in a Tertiary Hospital in South-Western Saudi Arabia: A Retrospective Study.

Purpose: To study the pattern of response to different treatment strategies in seropositive rheumatoid arthritis (RA) patients and to describe our clinical practice in RA management.

Patients And Methods: Over a period of two years from April 2018 to April 2020, we conducted a retrospective analysis of data for 288 consecutive seropositive RA patients attending rheumatology clinics and the daycare unit at Aseer Central Hospital. Data were collected on patient demographics, disease duration, extraarticular manifestations, comorbidities and treatment.

Small-Molecule Ferroptotic Agents with Potential to Selectively Target Cancer Stem Cells.

Effective management of advanced cancer requires systemic treatment including small molecules that target unique features of aggressive tumor cells. At the same time, tumors are heterogeneous and current evidence suggests that a subpopulation of tumor cells, called tumor initiating or cancer stem cells, are responsible for metastatic dissemination, tumor relapse and possibly drug resistance. Classical apoptotic drugs are less effective against this critical subpopulation.

The effects of experimentally induced graded monocular and binocular astigmatism on near stereoacuity.

Purpose: To determine the effects of experimentally induced graded monocular and binocular astigmatism on near Stereoacuity in healthy adults.

Method: This prospective cross-sectional study was performed on 60 healthy adults ranging between 19 and 33 years of age recruited from College of Applied Medical Sciences. All subjects were emmetropic with normal binocular single vision, and stereoacuity of 40 sec of arc.

Selective and super-selective C-arm based cone beam CT angiography (CBCTA) with DynaCT for CyberKnife radiosurgery planning of intracranial arteriovenous malformations (AVMs).

Background: Successful radiosurgery for intracranial arteriovenous malformations (AVMs) requires accurate delineation of the nidus in 3D. Exact targeting and precise equipment is needed to achieve obliteration of the nidus while minimizing toxicity to the surrounding brain. In some micro-AVMs and poorly visible AVMs we have used cone beam CT angiography (CBCTA) with selective and super-selective angiography where a micro-catheter is advanced into the feeding arteries- to assist with nidus definition for CyberKnife radiosurgery planning.

Transient in-stent stenosis at mid-term angiographic follow-up in patients treated with SILK flow diverter stents: incidence, clinical significance and long-term follow-up.

Background: Little is known about in-stent stenosis (ISS) in patients with aneurysms treated with flow diverter (FD) stents. The reported incidence in the literature varies significantly.

Objective: The aim of this study was to assess the incidence, severity, distribution, clinical significance, and possible predictors for ISS.

Small-molecule anticancer agents kill cancer cells by harnessing reactive oxygen species in an iron-dependent manner.

In the course of generating a library of open-chain epothilones, we discovered a new class of small molecule anticancer agents that has no effect on tubulin but instead kills selected cancer cell lines by harnessing reactive oxygen species in an iron-dependent manner. Results of the preliminary studies are consistent with the recently described cell death mechanism ferroptosis. Studies are in progress to confirm ferroptosis as the cell death mechanism and to identify the specific molecular targets of these small molecule anticancer agents.