Publications by authors named "Hanalise V Huff"
Pathogens with affinity for the central nervous system (CNS) in children are diverse in their mechanisms of infecting and attacking the brain. Infections can reach the CNS via hematogenous routes, transneurally thereby avoiding the blood-brain barrier, and across mucosal or skin surfaces. Once transmission occurs, pathogens can wreak havoc both by direct action on host cells and via an intricate interplay between the protective and pathologic actions of the host's immune system.
View Article and Find Full Text PDFThis scoping review aims to explore the interplay between substance use (SU) and HIV in Latin America (LA). Database searches yielded 3481 references; 196 were included. HIV prevalence among people who used substances (PWUS) ranged from 2.
View Article and Find Full Text PDFNeurocysticercosis (NCC) is a leading cause of preventable epilepsy in lower- and upper- middle-income countries (LMICs/UMICs). NCC is a human-to-human transmitted disease caused by ingestion of eggs from a carrier. infection control is the key to reduce NCC incidence.
View Article and Find Full Text PDFArticle Synopsis
- Newborn screening (NBS) is an effective public health strategy in developed countries but poses unique challenges in developing countries, particularly in Latin America, where ethical issues are complicated by population diversity.
- The expansion of NBS to include more conditions raises ongoing ethical considerations, especially concerning access to treatments for rare diseases identified through enhanced screening methods.
- Addressing global health disparities and ensuring optimal outcomes for newborns requires a tailored approach to NBS that respects the unique characteristics of each region rather than relying solely on universal ethical frameworks.
. The developing world continues to face challenges in closing the large treatment gap for epilepsy, due to a high burden of disease and few experienced providers to manage the condition. Children with epilepsy are susceptible to higher rates of developmental impairments and refractory disease due to delays or absence of appropriate management as a result.
View Article and Find Full Text PDFSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread rapidly in a few months despite global public health strategies to curb transmission by testing symptomatic patients and social distancing. This review summarizes evidence that highlights transmission by asymptomatic and presymptomatic individuals. Viral load of asymptomatic and symptomatic cases is comparable.
View Article and Find Full Text PDFObjectives: In children with clinically diagnosed learning disabilities with focal findings on neurologic or neuropsychological evaluations, there is a hypothesized association between disorders in automaticity and focal structural abnormalities observed in brain MRIs.
Methods: We undertook a retrospective analysis of cases referred to a tertiary-hospital-based learning disabilities program. Individuals were coded as having a focal deficit if either neurologic or neuropsychological evaluation demonstrated focal dysfunction.