Protein adsorption and cell adhesion behavior of engineering plastics plasticized by supercritical carbon dioxide.

We aimed to evaluate the biological properties of engineering plastics (PC, PSU, PAR) processed using supercritical carbon dioxide (scCO). Conventional mold process was used to prepare disk-shaped samples that were then plasticized by scCO at temperatures lower than the glass transition temperature (T) of the polymers. Surface roughness, contact angle, and amount of adsorbed protein on the surface were increased after treatment.

Effects of TGF‑β1 on the migration and morphology of RAW264.7 cells in vitro.

Osteoclasts (OCs) differentiate from monocyte/macrophage‑lineage hematopoietic precursor cells, which are known as OC precursors (OCPs). Several studies have investigated cell chemotaxis in the bone microenvironment; however, OCP migration ability in the bone microenvironment during OC differentiation is yet to be elucidated. As an initial investigation of this characteristic, the present study aimed to determine the effects of transforming growth factor (TGF)‑β1 on OCP migration in vitro.

Osteonecrosis of the jaws caused by bisphosphonate treatment and oxidative stress in mice.

Aging is a significant risk factor for the development of bisphosphonate-related osteonecrosis of the jaws (BRONJ). Accumulating evidence suggests that bone aging is associated with oxidative stress (OS), and OS is associated with osteonecrosis. To elucidate the mechanisms of the onset of BRONJ, the present study focused on OS and the effects of treatment with the pro-oxidant DL-buthionine-(S,R)-sulfoximine (BSO), an oxidative stressor, on healing of a surgically induced penetrating injury of the palate.