Publications by authors named "Hanaa K Ashour"
Novel and effective treatments are urgently needed for cancer, which is still the leading cause of death in the world. Biological characteristics linked to thiazole derivatives span a wide range. Thiazole derivatives are used in the creation of medications for therapy as well.
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- Researchers have developed new phthalazine derivatives and tested their effectiveness against cancer cells, focusing on drugs that can target the epidermal growth factor receptor (EGFR).
- The new compounds were synthesized by linking phthalazine with different heterocyclic systems and tested for their antiproliferative activity, showing promising results, especially against the HepG2 cell line.
- In vivo results also indicated significant activity of certain compounds compared to standard drugs, suggesting their potential as new lead candidates for cancer treatment.