Synthesis and Spectrum of Biological Activities of Novel N-arylcinnamamides.

A series of sixteen ring-substituted -arylcinnamamides was prepared and characterized. Primary in vitro screening of all the synthesized compounds was performed against , three methicillin-resistant strains, H37Ra, , and . Several of the tested compounds showed antistaphylococcal, antitubercular, and antifungal activities comparable with or higher than those of ampicillin, isoniazid, and benomyl.