Synopsis of recent research by authors named "Han-zhen Yuan"
- Han-Zhen Yuan's recent research focuses on cancer biology, specifically the inhibition of the hypoxia-inducible factor-1α (HIF-1α) pathway to target tumor angiogenesis and growth, as evidenced by the development of Panaxadiol derivatives with thiazole moieties exhibiting potential anti-tumor activity.
- Another significant area of Yuan's investigation is the prognostic role of GNG5 gene in gliomas, utilizing weighted gene co-expression network analysis to identify its unfavorable correlation with glioma progression, enhancing understanding of these common brain tumors.
- Yuan's foundational work also includes the analysis of mixed micelles through 1H NMR techniques, exploring the interactions between nonionic and ionic surfactants, which contributes to the study of surfactant systems and their applications in various fields.