Publications by authors named "Han-shen Zhen"
Sedum emarginatum Migo (Aoyejingtian) is a perennial succulent herb of the sedum genus in the family Crassulaceae, which has the fountion of treating furuncle, swelling and haematemesis, hematochezia, menorrhagia and hepatitis. Preliminary studies of our research group had showed that the ethyl acetate extract of Sedum emarginatum Migo could inhibit the proliferation of liver cancer HepG2 cells. The establishment of a reasonable and feasible quality evaluation method for the effective parts of Sedum emarginatum Migo can provide a scientific basis for the further development and utilization of Sedum emarginatum Migo.
View Article and Find Full Text PDFObjective: To study the macroscopic and microscopic characteristics of Zhuang medicine Tetrastigma planicaule.
Methods: Macroscopic and microscopic identification were studied.
Results: The microscopic characteristics were significant.
Objective: To analyze the volatile components from flowers of Gymnema sylvestre.
Methods: Volatile components of flowers of Gymnema sylvestre were extracted by water vapor distilling, and the components were separated and identified by GC-MS.
Results: 55 components were separated and 33 components were identified, accounting for 88.
Objective: To study the chemical constituents of petroleum ether portion from Seed of Picria felterrae.
Methods: The chemical constituents were extracted and isolated with solvent and chromatography, and the chemical structures were determined on the basis of physicochemical properties and spectral data (UV, IR, 1H-NMR, 13C-NMR, MS).
Results: Six chemical constituents were identified as follows: chrysophanol (I), 1-hydroxy-6-methyl-anthraquinone (II), beta-sitosterol (III), betulin (IV), N-benzoyl-phenylalanyl-L-phenylalaninol acetate (V) and picfeltarraenone I (VI).
Objective: To study the chemical constituents of the petroleum ether portion of Nervilia fordii.
Methods: The constituents were separated and purified by using column chromatography with silica gel. These compounds were identified by their physical and spectral data.
Objective: To establish the fingerprint spectrum of the stems of Actinidia deliciosa by HPLC.
Methods: HPLC fingerprint analysis of the stems of Actinidia deliciosa was developed and the thermo Hypersil BDS C18 column (250 mm x 4.6 mm, 5 microm) was used.
[Experimental [corrected] study of hypoglycemic activity of conduritol A of stems of Gymnema sylvestre].
Zhongguo Zhong Yao Za Zhi
December 2008
Objective: To investigates the mechanism of hypooglycemic effect of conduritol A of stems of Gymnema sylvestre.
Method: Fourteen days later after administration, observation is taken on the change of these mice and rats weight, the FBG, TG, CHO, SOD, MDA, INS, TNF in serum were also detected with enzymology method and Radioimmuoassay method. Take the liver to determine the disposal of glucose.
Objective: To study on the chemical constituents from the stem of Gymnema sylvestre.
Methods: The constituents were extracted by percolation with ethanol. Then the extract was separated by systemic solvent separation methods.
Objective: To study the chemical constituents of n-butyl alcohol extract in the roots of Actinidia deliciosa in Guangxi.
Method: The constituents were separated with various chromatographic techniques and their structures were elucidated by means of physicochemical properties and the analysis of their spectral data.
Result: Six compounds were isolated and identified as eriantic acid B (1), 2alpha, 3beta, 24-trihydroxyursa-12-en-28-oic acid (2), 2alpha, 3alpha, 24-trihydroxyursa-12-en-28-oic acid (3), 2alpha, 3alpha, 23-tri-hydroxyursa-12, 20 (30)-dien-28-oic acid (4), 2alpha, 3alpha, 24-trihydroxyursa-12, 20 (30)-dien-28-oic acid (5), n-butyl-O-beta-D-fruto-pyranoside (6).
Objective: To analyze the volatile oils chemical constituents of roots of Actinidia deliciosa.
Methods: The volatile oils fraction of roots of Actinidia deliciosa. were extracted by water vapor distilling, and then the constituents were separated and identified, by GC-MS.
Objective: To study the anti-tumor effect of ADEE and ADBE in mice.
Methods: The models of S180 entity tumor mice and H22 bearing tumor mice were established to observe the effect of ADEE and ADBE on inhibiting S180 entity tumor growth and prolonging life time of H22-mice, and the effect on spleen and thymus index to S180 entity tumor.
Results: Both ADEE and ADBE had ohvious anti-tumor effects to S180-mice (P < 0.
Article Synopsis
- The study aimed to identify the active components of Nervilia fordii that have anticancer effects in live mice models.
- Both petroleum ether and ethyl acetate extracts were found to significantly combat cancer in S180-mice and H22-mice, improving their lifespan and immune response.
- This research is the first to demonstrate the anticancer properties of these specific extracts from Nervilia fordii in vivo, suggesting the need for further study on their active compounds and characteristics.
Objective: To study the chemical constituents of the ethyl acetate portion in the herb of Nervilia fordii from guangxi.
Methods: The constituents were separated and purified by using column chromatography with silica gel. These compounds were identified by their physical and spectral data.