Nitrogen mustards (NMs) are an important class of chemotherapeutic drugs and have been widely employed for the treatment of various cancers. However, due to the high reactivity of nitrogen mustard, most NMs react with proteins and phospholipids within the cell membrane. Therefore, only a very small fraction of NMs can reach the reach nucleus, alkylating and cross-linking DNA.
View Article and Find Full Text PDFIn order to study the variation of water-soluble inorganic ions in the four suburbs of Beijing using the atmospheric fine particulate matter rapid trapping system and chemical composition analysis system (RCFP-IC), we carried out measurements for nine water-soluble inorganic ions (Cl, NO, NO, SO, Na, NH, K, Mg, Ca) in PM with continuous on-line observations for one year in Beijing's southern suburbs in 2016. The transport process of pollutants and the potential sources of pollutants were evaluated by combining a trajectory clustering method and potential source contribution factor analysis method (PSCF). During the observation period, the total concentration of the nine water-soluble inorganic ions was 38.
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