Publications by authors named "Han-Ying Jhuang"
Much of our understanding of functional genomics derives from insights gained from large strain libraries including the yeast deletion collection, the GFP and TAP-tagged libraries, QTL mapping populations, among others [1-5]. A limitation of these libraries is that it is not easy to introduce reporters or make genetic perturbations to all strains in these collections. Tools such as Synthetic Genetic Arrays allow for the genetic manipulation of these libraries but are labor intensive and require specialized equipment for high throughput pinning [6].
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- Determining the location history of objects is important for health, commerce, and food safety, and using microbes can provide a cost-effective way to track provenance.
- Researchers developed a scalable microbial spore system capable of identifying object origins in under an hour, achieving high sensitivity and environmental safety.
- This system addresses challenges like persistence, scalability, and rapid detection, and is compatible with SHERLOCK technology for diverse applications.
Mitochondrial-nuclear incompatibility has a major role in reproductive isolation between species. However, the underlying mechanism and driving force of mitochondrial-nuclear incompatibility remain elusive. Here, we report a pentatricopeptide repeat-containing (PPR) protein, Ccm1, and its interacting partner, 15S rRNA, to be involved in hybrid incompatibility between two yeast species, Saccharomyces cerevisiae and Saccharomyces bayanus S.
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