Publications by authors named "Han-Seung Shinf"
Eur J Pharm Sci
June 2016
Article Synopsis
- The study synthesizes a compound derived from chrysin, incorporating piperazine moieties, and evaluates its antioxidant and anticancer properties.
- The synthesized compounds showed significant antioxidant activity, particularly notable in specific analogs (7f, 7j, 7k, 7l, 7n, 7q, 7v, 7w) and strong anticancer effects against cervical and ovarian cancer cell lines (HeLa, CaSki, SK-OV-3).
- Importantly, the compounds exhibited low toxicity towards human bone marrow-derived mesenchymal stem cells, indicating they may be safer therapeutic candidates, while the effectiveness is linked to the functional groups on the piperazine core.
