[Effect of vimentin on activation of NLRP3 inflammasome in the brain of mice with EV71 infection].

Objective: To explore whether vimentin (VIM) mediates the activation of inflammasome in mice with EV71 infection in the central nervous system.

Methods: Forty VIM knockout mice (VIM, 3 to 5 days old) were randomly divided into control group and infection group. The infection group was intraperitoneally injected with EV71 (10 TCID), while the control group was injected with PBS (10 µL); another 40 wild-type mice (WT, 3 to 5 days old) were grouped in the same manner.