Publications by authors named "Han-Sen Lin"
Article Synopsis
- - Researchers found that a natural compound called (+)-Balasubramide has anti-inflammatory properties but doesn't work well for treating acute lung injury (ALI) due to poor absorption in the body.
- - A new derivative, called (+)3C-20, was developed and shows significantly better anti-inflammatory effects and absorption, specifically targeting inflammatory responses in both mouse and human immune cells.
- - The study revealed that (+)3C-20 works by inhibiting mitochondrial VDAC1, which helps stop the activation of inflammatory pathways, suggesting it could be an effective treatment for ALI.
Clear cell renal cell carcinoma (ccRCC) is the most common histological and devastating subtype of renal cell carcinoma. Necroptosis is a form of programmed cell death that causes prominent inflammatory responses. miRNAs play a significant role in cancer progression through necroptosis.
View Article and Find Full Text PDFHighly enantioselective synthesis of α,β-epoxy esters was achieved via one-pot organocatalytic epoxidation and consequent oxidative esterification. Excellent enantioselectivities (up to 99% ee) and good yields were obtained for a variety of α,β-epoxy esters. The method was readily scaled.
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